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Grupo de investigación Bioorgánica (BIOORG)

 
 
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Inhibition of human enhancer of zeste homolog 2 with tambjamine analogs

1,8-Diamidocarbazoles: an easily tuneable family of fluorescent anion sensors and transporters

Anion transport and supramolecular medicinal chemistry

Complementary regioselectivity in the synthesis of iminohydantoins: remarkable effect of amide substitution on the cyclization

Experimental and theoretical studies on the effect of the oxo group in 1,4-benzodiazepines

Transmembrane anion transport and cytotoxicity of synthetic tambjamine analogs

Novel indole-based tambjamine-analogues induce apoptotic lung cancer cell death through p38 mitogen-activated protein kinase activation

Anion-transport mechanism of a triazole-bearing derivative of prodigiosine: a candidate for cystic fibrosis therapy

Small molecule anionophores promote transmembrane anion permeation matching CFTR activity

Colonization of electrospun polycaprolactone fibers by relevant pathogenic bacterial strains

Polymeric chemosensor for the detection and quantification of chloride in human sweat. Application to the diagnosis of cystic fibrosis

QSAR analysis of substituent effects on tambjamine anion transporters

Reversal of diastereoselectivity in the synthesis of Peptidomimetic 3‑Carboxamide-1,4-benzodiazepin-5-ones

Synthetic tambjamine analogues induce mitochondrial swelling and lysosomal dysfunction leading to autophagy blockade and necrotic cell death in lung cancer

Molecular Interactions of Prodiginines with the BH3 Domain of Anti-Apoptotic Bcl-2 Family Members

A Practical, One-Pot Synthesis of Highly Substituted Thiophenes and Benzo[b]thiophenes from Bromoenynes and o-Alkynylbromobenzenes

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