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Título : Molecular Investigation of Tularemia Outbreaks, Spain, 1997–2008
Autor : Ariza Miguel, Jaime
Johansson, Anders
Fernández Natal, Isabel
Martínez Nistal, Carmen
Orduña, Antonio
Rodríguez Ferri, F.
Hernández, Marta
Rodríguez Lázaro, David
Publicado en: Emerging Infectious Diseases. 2014, V. 20, n. 5, p. 754-761
Editorial : Centers for Disease Control and Prevention
Fecha de publicación : may-2014
Resumen : Tularemia outbreaks occurred in northwestern Spain in 1997–1998 and 2007–2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable number tandem repeat analysis of 16 genomic loci of Francisella tularensis, the cause of this disease. Isolates were divided into 3 pulsotypes by pulsed-field gel electrophoresis and 8 allelic profiles by multilocus variable number tandem repeat analysis. Isolates obtained from the second tularemia outbreak had the same genotypes as isolates obtained from the first outbreak. Both outbreaks were caused by genotypes of genetic subclade B.Br:FTNF002–00, which is widely distributed in countries in central and western Europe. Thus, reemergence of tularemia in Spain was not caused by the reintroduction of exotic strains, but probably by persistence of local reservoirs of infection.
URI : http://hdl.handle.net/10259/4411
Versión del editor: https://dx.doi.org/10.3201/eid2005.130654
Aparece en las colecciones: Artículos TECNOFOOD

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