https://hdl.handle.net/10259/10182 2026-05-14T15:38:42Z 2026-05-14T15:38:42Z Antunes, Ana Cristina dos Santos Santamaría Peláez, Mirian Alcalá-Cerrillo, María Gentil Gutiérrez, Ana Amparo Vélez Santamaría, Rodrigo https://hdl.handle.net/10259/11613 2026-05-14T00:05:39Z 2026-03-01T00:00:00Z

Portuguese translation, cultural adaptation and pilot validation of HAND-Q Life Impact Scale Antunes, Ana Cristina dos Santos; Santamaría Peláez, Mirian; Alcalá-Cerrillo, María; Gentil Gutiérrez, Ana Amparo; Vélez Santamaría, Rodrigo Purpose: HAND-Q Life Impact Scale assesses how hand conditions affect quality of life, and it has not yet been translated nor validated for the Portuguese population. The aim is to translate, culturally and linguistically adapt, and pilot validate the HAND-Q Life Impact Scale for the Portuguese population. Materials and methods: Multicenter study involving translation, cultural and linguistic adaptation following International Society for Pharmacoeconomics and Outcomes Research guidelines (ISPOR) and pilot psychometric properties testing, at Physiatry and Occupational Therapy departments in rehabilitation centers in Portugal. 15 patients with hand conditions for cognitive interviews, 7 experts reviewed the scale, and 30 patients for pilot validation study. Results: The HAND-Q Life Impact Scale demonstrated excellent internal consistency (α = 0.891) with most items showing good item-total and inter-item correlations. A good degree of agreement was obtained among the experts. Significant correlations with upper limb disability and health related quality of life supported its validity. Conclusion: The Portuguese version of the HAND-Q Life Impact Scale appears to be reliable and valid for assessing the impact of hand conditions on quality of life, but further studies should confirm the findings. This research introduces the first validated Portuguese version of the HAND-Q Life Impact Scale.

2026-03-01T00:00:00Z Ramos-Hernández, Rafael Busto Vázquez, Natalia Miguel Ortega, Alvaro Martínez Ferrán, María Santamaría Peláez, Mirian Saiz Rodríguez, Miriam Mielgo Ayuso, Juan https://hdl.handle.net/10259/11612 2026-05-14T06:37:58Z 2026-01-01T00:00:00Z

Combined creatine and β-hydroxy-β-methylbutyrate supplementation with integral conditioning exercise enhances functional performance and metabolic health in physically active older adults: A randomized controlled crossover trial Ramos-Hernández, Rafael; Busto Vázquez, Natalia; Miguel Ortega, Alvaro; Martínez Ferrán, María; Santamaría Peláez, Mirian; Saiz Rodríguez, Miriam; Mielgo Ayuso, Juan Objective: to investigate the effects of six weeks of CRE + HMB supplementation integrated with a supervised multicomponent exercise program on functional performance, metabolic efficiency, and physiological health in older adults. Conclusions: six weeks of CRE + HMB supplementation integrated with supervised multicomponent training enhanced mobility, metabolic efficiency, and selected physiological outcomes in physically active older adults. This strategy represents a safe, feasible, and practical approach to sustain functional independence and metabolic health with aging.

2026-01-01T00:00:00Z Fernández Solana, Jessica Vélez Santamaría, Rodrigo Moreno-Villanueva, Adrián Álvarez Pardo, Sergio González Bernal, Jerónimo Santamaría Peláez, Mirian González Santos, Josefa https://hdl.handle.net/10259/10915 2025-10-03T00:05:32Z 2025-09-01T00:00:00Z

Effect of Mirror Therapy Versus Cognitive Therapeutic Exercise on Upper Limb Functionality, Autonomy, and Poststroke Quality of Life: A Randomized Trial Fernández Solana, Jessica; Vélez Santamaría, Rodrigo; Moreno-Villanueva, Adrián; Álvarez Pardo, Sergio; González Bernal, Jerónimo; Santamaría Peláez, Mirian; González Santos, Josefa Importance: A combination of rehabilitation techniques may be useful to optimize individualized treatment and efficient resource utilization. Objective: To assess the effect of cognitive therapeutic exercise (CTE) and mirror therapy (MT) combined with task-oriented training (TOT) on upper limb functionality, fine and gross motor skills, use of the paretic arm, functional independence in activities of daily living (ADLs), and quality of life among people with subacute stroke. Design: Randomized trial, longitudinal, and multicenter study with one control group (CG) and two experimental groups (EGs) who were assessed before, after, and 3 mo posttreatment. Setting: University of Burgos and Burgos University Hospital, Burgos, Spain. Participants: One hundred twenty patients with subacute stroke and motor symptoms in the upper limb recruited through consecutive nonprobabilistic sampling and excluding those with tremor due to another neurological disease or cognitive impairment. Intervention: MT + TOT (EG1) and CTE + TOT (EG2) over 20 1-hr sessions. T3he CG received usual therapy (TOT) that simulated everyday situations. Outcomes and Measures: The studied variables were evaluated with the Action Research Arm Test, Box and Block Test, Motor Activity Log, FIM™–Functional Assessment Measure, and Stroke-Specific Quality of Life Scale. Results: Statistically significant differences were found between the CG group and both EGs, with improvements in upper limb functionality, fine and gross motor skills, use of the paretic arm, functional independence in ADLs, and quality of life. No differences were found between EGs. Conclusions and Relevance: Application of these combined interventions improved all variables studied. Plain-Language Summary: This study found that the use of cognitive therapeutic exercise and mirror therapy combined with task-oriented training may improve upper limb functionality, fine and gross motor skills, the use of the paretic arm, functional independence in activities of daily living, and quality of life among people with subacute stroke.

2025-09-01T00:00:00Z Jiménez Barrios, María González Bernal, Jerónimo Santamaría Peláez, Mirian Collazo Riobó, Carla Cubo Delgado, Esther Trejo Gabriel y Galán, José Mª Matthews, Martin J. A. González Santos, Josefa https://hdl.handle.net/10259/10180 2025-02-08T01:05:24Z 2025-01-01T00:00:00Z

Impact of a Dynamic Orthosis on Manual Dexterity Among People With Parkinson’s Disease: A Randomized Trial Jiménez Barrios, María; González Bernal, Jerónimo; Santamaría Peláez, Mirian; Collazo Riobó, Carla; Cubo Delgado, Esther; Trejo Gabriel y Galán, José Mª; Matthews, Martin J. A.; González Santos, Josefa Importance: A dynamic elastomeric fabric orthosis could be a novel nonpharmacological treatment of motor symptoms among people with Parkinson’s disease (PD). Objective: To evaluate the efficacy of the orthosis in improving manual dexterity among people with PD. Design: A randomized trial with 60 participants (control group, n = 20; experimental group, n = 40). Manual dexterity was assessed in on–off states of the disease, with and without the orthosis. Setting: Burgos University Hospital (Burgos, Spain). Participants: Consecutive nonprobabilistic sampling. Patients were included if they had been diagnosed with PD, had motor symptoms in at least one upper limb, and attended the hospital’s neurology department. Participants were ages 48 to 89 yr, with an average disease duration of 5.38 yr (SD = 4.23). Exclusion criteria were tremor due to another neurological disease or a Montreal Cognitive Assessment score ≤26. Intervention: The experimental group used the orthosis on the most affected upper limb for 2 mo; the control group participants did not receive the orthosis. Outcomes and Measures: Manual dexterity was measured with the Purdue Pegboard Test, Minnesota Manual Dexterity Test, and Square Test. Paired t tests for related samples and analysis of covariance tests were used. Results: Some participants improved on some manual dexterity items while wearing the orthosis. However, it was not sustained when the orthosis was removed after 2 mo of use. Conclusions and Relevance: The orthosis may improve certain aspects of manual dexterity and functionality among people with PD, but only while it is worn. Plain-Language Summary: The common motor symptoms and declines in manual dexterity that people with Parkinson’s disease (PD) experience can significantly affect their ability to perform activities of daily living as well as their quality of life. Manual dexterity is a strong predictor of the level of functional independence for people with PD. This study evaluated the efficacy of an elastomeric fabric orthosis to improve manual dexterity for people with PD. The study found that while wearing the orthosis the motor symptoms of PD were reduced and manual dexterity and upper limb functionality improved. Wearing the orthosis has the potential to enhance functionality, foster greater autonomy, and substantially improve the quality of life of people with PD.

2025-01-01T00:00:00Z