https://hdl.handle.net/10259/6688 2026-04-18T11:08:20Z https://hdl.handle.net/10259/10180 Impact of a Dynamic Orthosis on Manual Dexterity Among People With Parkinson’s Disease: A Randomized Trial Jiménez Barrios, María; González Bernal, Jerónimo; Santamaría Peláez, Mirian; Collazo Riobó, Carla; Cubo Delgado, Esther; Trejo Gabriel y Galán, José Mª; Matthews, Martin J. A.; González Santos, Josefa Importance: A dynamic elastomeric fabric orthosis could be a novel nonpharmacological treatment of motor symptoms among people with Parkinson’s disease (PD). Objective: To evaluate the efficacy of the orthosis in improving manual dexterity among people with PD. Design: A randomized trial with 60 participants (control group, n = 20; experimental group, n = 40). Manual dexterity was assessed in on–off states of the disease, with and without the orthosis. Setting: Burgos University Hospital (Burgos, Spain). Participants: Consecutive nonprobabilistic sampling. Patients were included if they had been diagnosed with PD, had motor symptoms in at least one upper limb, and attended the hospital’s neurology department. Participants were ages 48 to 89 yr, with an average disease duration of 5.38 yr (SD = 4.23). Exclusion criteria were tremor due to another neurological disease or a Montreal Cognitive Assessment score ≤26. Intervention: The experimental group used the orthosis on the most affected upper limb for 2 mo; the control group participants did not receive the orthosis. Outcomes and Measures: Manual dexterity was measured with the Purdue Pegboard Test, Minnesota Manual Dexterity Test, and Square Test. Paired t tests for related samples and analysis of covariance tests were used. Results: Some participants improved on some manual dexterity items while wearing the orthosis. However, it was not sustained when the orthosis was removed after 2 mo of use. Conclusions and Relevance: The orthosis may improve certain aspects of manual dexterity and functionality among people with PD, but only while it is worn. Plain-Language Summary: The common motor symptoms and declines in manual dexterity that people with Parkinson’s disease (PD) experience can significantly affect their ability to perform activities of daily living as well as their quality of life. Manual dexterity is a strong predictor of the level of functional independence for people with PD. This study evaluated the efficacy of an elastomeric fabric orthosis to improve manual dexterity for people with PD. The study found that while wearing the orthosis the motor symptoms of PD were reduced and manual dexterity and upper limb functionality improved. Wearing the orthosis has the potential to enhance functionality, foster greater autonomy, and substantially improve the quality of life of people with PD. 2025-01-01T00:00:00Z https://hdl.handle.net/10259/10135 Adenocarcinoma on retrorectal cystic hamartoma: An illustrative image for a very rare diagnosis Reoyo Pascual, José Felipe; Alonso Alonso, Evelio; Polanco Pérez, Lucía; Álvarez Rico, Miguel Ángel Retrorectal cystic hamartoma (also known as tailgut cyst) is a congenital lesion that originates from debris from the embryonic caudal intestine. Incidentally diagnosed in more than half of cases, the treatment of choice is surgical resection. It is a very rare pathology whose oncological transformation constitutes a true pathological rarity. 2024-12-01T00:00:00Z https://hdl.handle.net/10259/10134 Predictors for Anastomotic Leak, Postoperative Complications, and Mortality After Right Colectomy for Cancer: Results From an International Snapshot Audit Frasson, Matteo; Battersby, Nick J.; Reoyo Pascual, José Felipe; 2015 European Society of Coloproctology Collaborating Group BACKGROUND: A right hemicolectomy is among the most commonly performed operations for colon cancer, but modern high-quality, multination data addressing the morbidity and mortality rates are lacking. OBJECTIVE: This study reports the morbidity and mortality rates for right-sided colon cancer and identifies predictors for unfavorable short-term outcome after right hemicolectomy. DESIGN: This was a snapshot observational prospective study. SETTING: The study was conducted as a multicenter international study. PATIENTS: The 2015 European Society of Coloproctology snapshot study was a prospective multicenter international series that included all patients undergoing elective or emergency right hemicolectomy or ileocecal resection over a 2-month period in early 2015. This is a subanalysis of the colon cancer cohort of patients. MAIN OUTCOME MEASURES: Predictors for anastomotic leak and 30-day postoperative morbidity and mortality were assessed using multivariable mixed-effect logistic regression models after variables selection with the Lasso method. RESULTS: Of the 2515 included patients, an anastomosis was performed in 97.2% (n = 2444), handsewn in 38.5% (n = 940) and stapled in 61.5% (n = 1504) cases. The overall anastomotic leak rate was 7.4% (180/2444), 30-day morbidity was 38.0% (n = 956), and mortality was 2.6% (n = 66). Patients with anastomotic leak had a significantly increased mortality rate (10.6% vs 1.6% no-leak patients; p > 0.001). At multivariable analysis the following variables were associated with anastomotic leak: longer duration of surgery (OR = 1.007 per min; p = 0.0037), open approach (OR = 1.9; p = 0.0037), and stapled anastomosis (OR = 1.5; p = 0.041). LIMITATIONS: This is an observational study, and therefore selection bias could be present. For this reason, a multivariable logistic regression model was performed, trying to correct possible confounding factors. CONCLUSIONS: Anastomotic leak after oncologic right hemicolectomy is a frequent complication, and it is associated with increased mortality. The key contributing surgical factors for anastomotic leak were anastomotic technique, surgical approach, and duration of surgery. See Video Abstract at https://links.lww.com/DCR/B165.; ANTECEDENTES: La hemicolectomía derecha se encuentra entre las operaciones más frecuentemente realizadas para cáncer de colon, pero faltan datos modernos multinacionales de alta calidad, que aborden las tasas de morbilidad y mortalidad. OBJETIVO: Reportar la tasa de morbilidad y mortalidad para cáncer de colon del lado derecho, e identificar predictores de resultados desfavorables a corto plazo, después de la hemicolectomía derecha. DISEÑO: Estudio prospectivo observacional de corto plazo. LUGAR: Estudio multicéntrico internacional. PACIENTES: El estudio de corto plazo de la Sociedad Europea de Coloproctología de 2015, fue una serie prospectiva multicéntrica internacional, que incluyó a todos los pacientes sometidos a hemicolectomía derecha electiva, de emergencia o resección ileocecal, por un período de dos meses y a principios de 2015. Este es un subanálisis, cohorte de pacientes con cáncer de colon. PRINCIPALES MEDIDAS DE RESULTADO: Los predictores de fuga anastomótica, morbilidad y mortalidad postoperatorias a los 30 días, se evaluaron usando modelos de regresión logística de efectos multivariables mixtos, después de la selección de variables con el método Lasso. RESULTADOS: De los 2,515 pacientes incluidos, se realizó una anastomosis en el 97,2% (n = 2,444); sutura manual en 38.5% (n = 940) y por engrapadora en 61.5% (n = 1504) casos. La tasa global de fuga anastomótica fue del 7,4% (180/2,444), morbilidad a los 30 días fue del 38,0% (n = 956) y la mortalidad fue del 2,6% (n = 66). Los pacientes con fuga anastomótica tuvieron una tasa de mortalidad significativamente mayor (10,6% frente al 1,6% de pacientes sin fuga, p> 0,001). En el análisis multivariable, las siguientes variables se asociaron con la fuga anastomótica: mayor duración de la cirugía (OR 1.007 por minuto, p = 0.0037), abordaje abierto (OR 1.9, p = 0.0037) y anastomosis por engrapadora (OR 1.5, p = 0.041). LIMITACIONES: Este es un estudio observacional y por lo tanto podría estar presente el sesgo de selección. Por esta razón, se realizó un modelo de regresión logística multivariable, tratando de corregir posibles factores de confusión. CONCLUSIONES: La fuga anastomótica después de la hemicolectomía derecha oncológica, es una complicación frecuente y asociada a mayor mortalidad. Los factores quirúrgicos clave que contribuyeron a la fuga anastomótica, fueron la técnica anastomótica, abordaje quirúrgico y duración de la cirugía. Consulte Video Resumen en https://links.lww.com/DCR/B165. 2020-05-01T00:00:00Z https://hdl.handle.net/10259/10131 Pneumatosis cystoides intestinalis: driven by the symptoms Reoyo Pascual, José Felipe; Otero Rondón, Michelle; Muñoz Plaza, Nerea; Álvarez Rico, Miguel Pneumatosis cystoides intestinalis is an uncommon disease of uncertain etiology, defined as the presence of submucosal or subserosal gas cysts in the wall of the small or large bowel. It is usually a casual finding, with a wide array of symptoms, from diarrhea, pain or bloating, to bowel intussusception, volvulus or obstruction. 2023-01-01T00:00:00Z