https://hdl.handle.net/10259/4354 Fri, 17 Apr 2026 20:19:31 GMT 2026-04-17T20:19:31Z https://hdl.handle.net/10259/10163 Self-assembling Depsipeptides on Aggregation-Induced Emission Luminogens: A New Way to Create Programmable Nanovesicles and Soft Nanocarriers Hernando Muñoz, Carla; Revilla Cuesta, Andrea; Abajo Cuadrado, Irene; Andreini, Camilla; Torroba Pérez, Tomás; Busto Vázquez, Natalia; Fernández Zoppino, Darío; Perdomo Hernández, Germán M.; Acosta, Gerardo; Royo, Miriam; Gutiérrez Reguera, Javier; Spinello, Angelo; Barone, Giampaolo; Black, Dominic; Pal, Robert We introduce the proof of concept of a newmethodology to produce robust hollow nanovesicles stable inwater or mixtures of water and organic solvents. The bottom-upproduced nanovesicles are formed by the self-assembly ofdepsipeptide chains of natural origin combined with newaggregation-induced emission luminogens that function as constitu-tional vesicle-forming moieties and fluorescent indicators of thestructure of the nanovesicle. The newly formed nanovesicles arerobust enough to be used to carry large molecules such asphysiological peptides without losing their structural characteristics,acting as programmable nanocarrier systems within living cells asTrojan horse systems, constituting a new approach to activetransport and nanoencapsulation. Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10259/10163 2025-01-01T00:00:00Z https://hdl.handle.net/10259/8481 Interactive Computer Game That Engages Students in Reviewing Organic Compound Nomenclature Silva Júnior, José Nunes da; Nobre, Davi Janô; Nascimento, Rômulo Silva do; Torres, Giancarlo Schaffer; Leite, Antonio José Melo; Monteiro, André Jalles; Alexandre, Francisco Serra Oliveira; Rodríguez Rodríguez, Mª Teresa; Rojo Cámara, Mª Josefa This report provides information about an interactive computer game named Say My Name that allows high school and undergraduate students to review individually nomenclature of organic compounds in an engaging and fun way by answering up to 600 questions distributed in three difficulty levels. Responses from students and teachers who have played the game have been quite positive. An assessment of students’ knowledge gains was also performed; the results reveal that students who used the game as a complementary didactic tool in their studies had higher numbers of correct answers than did students who studied using conventional learning methods. Say My Name can be played in Portuguese, Spanish, and English online (free of charge) via a Web browser. Tue, 01 May 2018 00:00:00 GMT https://hdl.handle.net/10259/8481 2018-05-01T00:00:00Z https://hdl.handle.net/10259/8459 Palladium nanodendrites uniformly deposited on the surface of polymers as an efficient and recyclable catalyst for direct drug modification via Z-selective semihydrogenation of alkynes García Calvo, José; Calvo Gredilla, Patricia; Vallejos Calzada, Saúl; García Pérez, José Miguel; Cuevas Vicario, José Vicente; García Herbosa, Gabriel; Avella, Manuel; Torroba Pérez, Tomás The preparation of new monodisperse polycrystalline palladium nanoparticles uniformly distributed on the surface of polymers, by simply adding a palladium(II) solution in water to the polymers, is described. The polymer supported palladium nanoparticles material was used as an efficient portable and reusable catalyst for the stereoselective semihydrogenation reaction of internal alkynes to (Z)-alkenes in green solvents. Sun, 01 Jul 2018 00:00:00 GMT https://hdl.handle.net/10259/8459 2018-07-01T00:00:00Z https://hdl.handle.net/10259/8384 Surface functionalized silica nanoparticles for the off–on fluorogenic detection of an improvised explosive, TATP, in a vapour flow García Calvo, José; Calvo Gredilla, Patricia; Ibáñez Llorente, Marcos; Romero Velásquez, Daisy Carolina; Cuevas Vicario, José Vicente; García Herbosa, Gabriel; Avella, Manuel; Torroba Pérez, Tomás We report the development of new fluorogenic silica nanomaterials that were able to generate fluorescence in the presence of vapours of triacetone triperoxide, TATP, an improvised explosive used in terrorist attacks. The materials worked in a vapour flow of TATP, giving a permanent and strongly fluorescent response. Thu, 01 Feb 2018 00:00:00 GMT https://hdl.handle.net/10259/8384 2018-02-01T00:00:00Z