2026-04-18T14:56:29Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/100382025-01-25T01:05:39Zcom_10259_6688com_10259_5086com_10259_2604col_10259_6689
2025-01-24T11:56:38Z
urn:hdl:10259/10038
Epigenome-wide association study of COVID-19 severity with respiratory failure
Castro de Moura, Manuel
Davalos, Veronica
Planas-Serra, Laura
Alvarez-Errico, Damiana
Arribas, Carles
Ruiz, Montserrat
Aguilera-Albesa, Sergio
Troya, Jesús
Valencia Ramos, Juan
Vélez-Santamaria, Valentina
Rodríguez-Palmero, Agustí
Villar-Garcia, Judit
Horcajada, Juan P.
Albu, Sergiu
Casasnovas, Carlos
Rull, Anna
Reverte, Laia
Dietl, Beatriz
Dalmau, David
Arranz, Maria J.
Llucià-Carol, Laia
Planas, Anna M.
Pérez-Tur, Jordi
Fernandez-Cadenas, Israel
Villares, Paula
Tenorio, Jair
Colobran, Roger
Martin-Nalda, Andrea
Soler-Palacin, Pere
Vidal, Francesc
Pujol, Aurora
Esteller, Manel
Coronavirus
SARS-CoV-2
COVID-19
Epigenetics
DNA methylation
Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide spectrum of disease behaviour. Since DNA methylation has been implicated in the regulation of viral infections and the immune system, we performed an epigenome-wide association study (EWAS) to identify candidate loci regulated by this epigenetic mark that could be involved in the onset of COVID-19 in patients without comorbidities.
2025-01-24T11:56:38Z
2025-01-24T11:56:38Z
2021-04
info:eu-repo/semantics/article
2352-3964
http://hdl.handle.net/10259/10038
10.1016/j.ebiom.2021.103339
eng
eBioMedicine. 2021, V. 66, p. 103339
https://doi.org/10.1016/j.ebiom.2021.103339
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Elsevier