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<dc:title>Epigenome-wide association study of COVID-19 severity with respiratory failure</dc:title>
<dc:creator>Castro de Moura, Manuel</dc:creator>
<dc:creator>Davalos, Veronica</dc:creator>
<dc:creator>Planas-Serra, Laura</dc:creator>
<dc:creator>Alvarez-Errico, Damiana</dc:creator>
<dc:creator>Arribas, Carles</dc:creator>
<dc:creator>Ruiz, Montserrat</dc:creator>
<dc:creator>Aguilera-Albesa, Sergio</dc:creator>
<dc:creator>Troya, Jesús</dc:creator>
<dc:creator>Valencia Ramos, Juan</dc:creator>
<dc:creator>Vélez-Santamaria, Valentina</dc:creator>
<dc:creator>Rodríguez-Palmero, Agustí</dc:creator>
<dc:creator>Villar-Garcia, Judit</dc:creator>
<dc:creator>Horcajada, Juan P.</dc:creator>
<dc:creator>Albu, Sergiu</dc:creator>
<dc:creator>Casasnovas, Carlos</dc:creator>
<dc:creator>Rull, Anna</dc:creator>
<dc:creator>Reverte, Laia</dc:creator>
<dc:creator>Dietl, Beatriz</dc:creator>
<dc:creator>Dalmau, David</dc:creator>
<dc:creator>Arranz, Maria J.</dc:creator>
<dc:creator>Llucià-Carol, Laia</dc:creator>
<dc:creator>Planas, Anna M.</dc:creator>
<dc:creator>Pérez-Tur, Jordi</dc:creator>
<dc:creator>Fernandez-Cadenas, Israel</dc:creator>
<dc:creator>Villares, Paula</dc:creator>
<dc:creator>Tenorio, Jair</dc:creator>
<dc:creator>Colobran, Roger</dc:creator>
<dc:creator>Martin-Nalda, Andrea</dc:creator>
<dc:creator>Soler-Palacin, Pere</dc:creator>
<dc:creator>Vidal, Francesc</dc:creator>
<dc:creator>Pujol, Aurora</dc:creator>
<dc:creator>Esteller, Manel</dc:creator>
<dc:subject>Coronavirus</dc:subject>
<dc:subject>SARS-CoV-2</dc:subject>
<dc:subject>COVID-19</dc:subject>
<dc:subject>Epigenetics</dc:subject>
<dc:subject>DNA methylation</dc:subject>
<dc:subject>Medicina</dc:subject>
<dc:subject>Medicine</dc:subject>
<dc:description>Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide spectrum of disease behaviour. Since DNA methylation has been implicated in the regulation of viral infections and the immune system, we performed an epigenome-wide association study (EWAS) to identify candidate loci regulated by this epigenetic mark that could be involved in the onset of COVID-19 in patients without comorbidities.</dc:description>
<dc:date>2025-01-24T11:56:38Z</dc:date>
<dc:date>2025-01-24T11:56:38Z</dc:date>
<dc:date>2021-04</dc:date>
<dc:type>info:eu-repo/semantics/article</dc:type>
<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
<dc:identifier>2352-3964</dc:identifier>
<dc:identifier>http://hdl.handle.net/10259/10038</dc:identifier>
<dc:identifier>10.1016/j.ebiom.2021.103339</dc:identifier>
<dc:language>eng</dc:language>
<dc:relation>eBioMedicine. 2021, V. 66, p. 103339</dc:relation>
<dc:relation>https://doi.org/10.1016/j.ebiom.2021.103339</dc:relation>
<dc:rights>Attribution-NonCommercial-NoDerivatives 4.0 Internacional</dc:rights>
<dc:rights>http://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
<dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
<dc:format>application/pdf</dc:format>
<dc:publisher>Elsevier</dc:publisher>
<europeana:object>https://riubu.ubu.es/bitstream/10259/10038/4/Castro-ebm_2021.pdf.jpg</europeana:object>
<europeana:provider>Hispana</europeana:provider>
<europeana:type>TEXT</europeana:type>
<europeana:rights>http://creativecommons.org/licenses/by-nc-nd/4.0/</europeana:rights>
<europeana:dataProvider>RIUBU. Repositorio Institucional de la Universidad de Burgos</europeana:dataProvider>
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