2026-04-29T13:16:59Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/100482025-01-28T01:05:27Zcom_10259_6688com_10259_5086com_10259_2604col_10259_6689

Observational study of newborn infant parasympathetic evaluation as a comfort system in awake patients admitted to a pediatric intensive care unit Valencia Ramos, Juan Arnaez, Juan Calvo Meruelo, Sara Gomez, Fernando Blanco Gómez, Isabel del Comfort Newborn infant parasympathetic evaluation COMFORT Behavior Scale Nebulization Bronchiolitis Bronquiolitis Enfermedades infecciosas en niños Communicable diseases in children To compare the newborn infant parasympathetic evaluation system (NIPE) scores with a validated clinical scale using two different nebulizers in children with bronchiolitis admitted to a PICU. Comfort was evaluated using the COMFORT-behavior scale (CBS) before (T1), during (T2) and after (T3) each nebulization. In order to compare NIPE and CBS values during the whole T1 to T3 period, the variable Dif-CBS was defined as the difference between maximal and minimal CBS scores, and Dif-NIPE as the difference between 75th and 25th percentile NIPE values. Analyses were carried out, firstly for the total of nebulizations and secondly comparing two different nebulization systems: a jet nebulizer (JN) and a nebulizer integrated in high flow nasal cannulas (NHF). 84 nebulizations were recorded on 14 patients with a median [25th–75th percentile] age of 6 months (3.1–9.5). A Dif-CBS of 4 points (2–7), as well as changes in CBS scores between T1 and T2, defined the nebulization as a discomfort stimulus. The NIPE system, represented as the Dif-NIPE, showed a median variation of 9 points (7–10), and was poorly correlated to Dif-CBS [rs 0.162 (P = 0.142)]. Discomfort during nebulization, assessed by CBS was greater with the JN system compared to NHF: 17 (13–22) vs 13 (9–15) (P = 0.001). NIPE monitoring detected no significant differences between both nebulization systems (P = 0.706). NIPE monitoring showed a variation in comfort during nebulization in the patient with bronchiolitis, though correlation with CBS was poor. Further research is required before NIPE can be suggested as a comfort monitoring system for the awake infant. 2025-01-27T12:31:12Z 2025-01-27T12:31:12Z 2019-02 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion 1387-1307 http://hdl.handle.net/10259/10048 10.1007/s10877-019-00268-1 1573-2614 eng Journal of Clinical Monitoring and Computing. 2019, V. 33, n. 5, p. 749–755 https://doi.org/10.1007/s10877-019-00268-1 info:eu-repo/semantics/openAccess application/pdf Springer