2026-04-17T11:44:27Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/101632026-01-31T23:42:24Zcom_10259_4354com_10259_5086com_10259_2604col_10259_4355

00925njm 22002777a 4500 dc Hernando Muñoz, Carla author Revilla Cuesta, Andrea author Abajo Cuadrado, Irene author Andreini, Camilla author Torroba Pérez, Tomás author Busto Vázquez, Natalia author Fernández Zoppino, Darío author Perdomo Hernández, Germán M. author Acosta, Gerardo author Royo, Miriam author Gutiérrez Reguera, Javier author Spinello, Angelo author Barone, Giampaolo author Black, Dominic author Pal, Robert author 2025-01 We introduce the proof of concept of a newmethodology to produce robust hollow nanovesicles stable inwater or mixtures of water and organic solvents. The bottom-upproduced nanovesicles are formed by the self-assembly ofdepsipeptide chains of natural origin combined with newaggregation-induced emission luminogens that function as constitu-tional vesicle-forming moieties and fluorescent indicators of thestructure of the nanovesicle. The newly formed nanovesicles arerobust enough to be used to carry large molecules such asphysiological peptides without losing their structural characteristics,acting as programmable nanocarrier systems within living cells asTrojan horse systems, constituting a new approach to activetransport and nanoencapsulation. 1944-8244 http://hdl.handle.net/10259/10163 10.1021/acsami.4c19123 1944-8252 Fluorescent materials Aggregation induced emission materials Active transport Nanoencapsulation Programmed cytotoxity Self-assembling Depsipeptides on Aggregation-Induced Emission Luminogens: A New Way to Create Programmable Nanovesicles and Soft Nanocarriers