2026-04-18T07:36:49Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/101932025-07-28T11:57:58Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845
2025-02-10T09:21:00Z
urn:hdl:10259/10193
New screen-printed electrodes for Raman spectroelectrochemistry. Determination of p-aminosalicylic acid
Romay García, Luis
Núñez Marinero, Pello
Perales Rondon, Juan Víctor
Heras Vidaurre, Aránzazu
Campo García, Francisco Javier del
Colina Santamaría, Álvaro
Screen-printed electrodes
Raman spectroelectrochemistry
Electrochemistry
EC-SERS
EC-SOERS
4-Aminosalicylic acid
The availability of new surface enhanced Raman scattering (SERS) substrates is essential to develop
quantitative analytical methods. Electrochemistry is an easy, fast and reproducible methodology to prepare SERS
substrates on screen-printed electrodes (SPEs).
Results: This work proposes new SPEs based on a three-electrode system all made of silver. Using the same ink for
the whole electrode system facilitates the fabrication process, reduces production costs, and leads to excellent
analytical performance. The results showed that Raman enhancement depends strongly on the type of silver ink.
To demonstrate the capabilities of the new electrodes developed, 4-aminosalicylic acid was determined in
complex matrices and in the presence of strong interfering compounds such as salicylic acid and acetylsalicylic
acid. The proposed analytical method is based on the electrochemical surface oxidation enhanced Raman scat
tering (EC-SOERS) strategy. AgCl nanocrystals are generated on the working electrode surface, which amplify the Raman signal of 4-aminosalicylic acid. Good figures of merit were obtained both in the absence and in the
presence of the interfering compounds, achieving a correct estimation of a 4-aminosalicylic test sample in
complex matrices.
Significance: The new SPEs have been demonstrated to be very sensitive and reproducible which, together to the
high specificity of the Raman signal, makes this methodology very attractive for chemical analysis.
2025-02-10T09:21:00Z
2025-02-10T09:21:00Z
2024-10
info:eu-repo/semantics/article
0003-2670
http://hdl.handle.net/10259/10193
10.1016/j.aca.2024.343095
eng
Analytica Chimica Acta. 2024, V. 1325, p. 343095
https://doi.org/10.1016/j.aca.2024.343095
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2017-2020/PID2020-113154RB-C21/ES/APLICACION DE NUEVOS MATERIALES Y DISPOSITIVOS PARA EC-SERS Y EC-SOERS/
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2017-2020/PID2020-113154RB-C22/ES/DESARROLLO DE NUEVOS MATERIALES Y DISPOSITIVOS PARA EC-SERS y EC-SOERS/
info:eu-repo/grantAgreement/Junta de Castilla y León//BU036P23//Desarrollo de técnicas analíticas in-situ y en condiciones operando para el estudio de electrocatalizadores para la conversión electroquímica de nitrato de amoniaco/
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2021-2023/RED2022-134120-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS: RETOS ANTE LA TRANSFORMACION DIGITAL E INDUSTRIAL/
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
Atribución 4.0 Internacional
Elsevier