2026-04-18T07:37:04Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/101952025-07-28T07:49:33Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845
2025-02-10T09:21:26Z
urn:hdl:10259/10195
Determination of ofloxacin in urine using UV/Vis absorption spectroelectrochemistry
Olmo Alonso, Fabiola
Colina Santamaría, Álvaro
Heras Vidaurre, Aránzazu
Ofloxacin
Urine
Spectroelectrochemistry
Multivariate analysis
UV–Vis absorption spectroelectrochemistry has been selected as a suitable multiresponse technique to determine
the fluoroquinolone ofloxacin in urine samples without any previous pretreatment. Due to the modification of the
working electrode surface during the oxidation of this antibiotic, the electrode has to be replaced or polished
between measurements. A new spectroelectrochemistry cell has been developed, which allows in an simple way
to perform reproducible experiments with different screen-printed electrodes. The new cell has been used to
perform analysis in a complex matrix such as urine. Due to the trilinear character of the spectroelectrochemical
data, PARAFAC has been used to determine ofloxacin with very good figures of merit, demonstrating the
capability of trilinear methods to avoid the influence of some interfering compounds.
2025-02-10T09:21:26Z
2025-02-10T09:21:26Z
2024-03
info:eu-repo/semantics/article
0026-265X
http://hdl.handle.net/10259/10195
10.1016/j.microc.2024.110186
eng
Microchemical Journal. 2024, V. 198, 110186
https://doi.org/10.1016/j.microc.2024.110186
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2017-2020/PID2020-113154RB-C21/ES/APLICACION DE NUEVOS MATERIALES Y DISPOSITIVOS PARA EC-SERS Y EC-SOERS/
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2021-2023/RED2022–134120-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS: RETOS ANTE LA TRANSFORMACION DIGITAL E INDUSTRIAL/
info:eu-repo/grantAgreement/Junta de Castilla y León//BU036P23// DESARROLLO DE TÉCNICAS ANALÍTICAS IN-SITU Y EN CONDICIONES OPERANDO PARA EL ESTUDIO DE ELECTROCATALIZADORES PARA LA CONVERSIÓN ELECTROQUÍMICA DE NITRATO DE AMONIACO/
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
Atribución 4.0 Internacional
Elsevier