2026-04-18T07:35:46Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/101952025-07-28T07:49:33Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

Olmo Alonso, Fabiola Colina Santamaría, Álvaro Heras Vidaurre, Aránzazu 2025-02-10T09:21:26Z 2025-02-10T09:21:26Z 2024-03 0026-265X http://hdl.handle.net/10259/10195 10.1016/j.microc.2024.110186 UV–Vis absorption spectroelectrochemistry has been selected as a suitable multiresponse technique to determine the fluoroquinolone ofloxacin in urine samples without any previous pretreatment. Due to the modification of the working electrode surface during the oxidation of this antibiotic, the electrode has to be replaced or polished between measurements. A new spectroelectrochemistry cell has been developed, which allows in an simple way to perform reproducible experiments with different screen-printed electrodes. The new cell has been used to perform analysis in a complex matrix such as urine. Due to the trilinear character of the spectroelectrochemical data, PARAFAC has been used to determine ofloxacin with very good figures of merit, demonstrating the capability of trilinear methods to avoid the influence of some interfering compounds. Ministerio de Ciencia e Innovacion ´ and Agencia Estatal de Inves tigacion ´ (Grant numbers: MCIN/AEI/10.13039/501100011033, PID2020-113154RB-C21), Ministerio de Ciencia, Innovacion ´ y Uni versidades (Grant number: RED2022-134120-T), Junta de Castilla y Leon ´ and European Regional Development Fund (Grant number: BU036P23) are gratefully acknowledged for funding this work. application/pdf eng Elsevier Microchemical Journal. 2024, V. 198, 110186 https://doi.org/10.1016/j.microc.2024.110186 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2017-2020/PID2020-113154RB-C21/ES/APLICACION DE NUEVOS MATERIALES Y DISPOSITIVOS PARA EC-SERS Y EC-SOERS/ info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2021-2023/RED2022–134120-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS: RETOS ANTE LA TRANSFORMACION DIGITAL E INDUSTRIAL/ info:eu-repo/grantAgreement/Junta de Castilla y León//BU036P23// DESARROLLO DE TÉCNICAS ANALÍTICAS IN-SITU Y EN CONDICIONES OPERANDO PARA EL ESTUDIO DE ELECTROCATALIZADORES PARA LA CONVERSIÓN ELECTROQUÍMICA DE NITRATO DE AMONIACO/ Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Ofloxacin Urine Spectroelectrochemistry Multivariate analysis Química analítica Electroquímica Chemistry, Analytic Electrochemistry Determination of ofloxacin in urine using UV/Vis absorption spectroelectrochemistry info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Microchemical Journal 198 110186