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<dc:creator>Olmo Alonso, Fabiola</dc:creator>
<dc:creator>Colina Santamaría, Álvaro</dc:creator>
<dc:creator>Heras Vidaurre, Aránzazu</dc:creator>
<dc:date>2024-03</dc:date>
<dc:description>UV–Vis absorption spectroelectrochemistry has been selected as a suitable multiresponse technique to determine&#xd;
the fluoroquinolone ofloxacin in urine samples without any previous pretreatment. Due to the modification of the&#xd;
working electrode surface during the oxidation of this antibiotic, the electrode has to be replaced or polished&#xd;
between measurements. A new spectroelectrochemistry cell has been developed, which allows in an simple way&#xd;
to perform reproducible experiments with different screen-printed electrodes. The new cell has been used to&#xd;
perform analysis in a complex matrix such as urine. Due to the trilinear character of the spectroelectrochemical&#xd;
data, PARAFAC has been used to determine ofloxacin with very good figures of merit, demonstrating the&#xd;
capability of trilinear methods to avoid the influence of some interfering compounds.</dc:description>
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<dc:language>eng</dc:language>
<dc:publisher>Elsevier</dc:publisher>
<dc:title>Determination of ofloxacin in urine using UV/Vis absorption spectroelectrochemistry</dc:title>
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