2026-04-17T21:05:32Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/102292025-06-04T12:54:32Zcom_10259_3844com_10259_5086com_10259_2604col_10259_7686col_10259_5684

Olmo Alonso, Fabiola 775 600 Rodríguez Rubio, Andrea 4ec01ffa-3ba5-431a-b456-2f97c2f6c435 600 Colina Santamaría, Álvaro 122 600 0000-0003-0339-356X Heras Vidaurre, Aránzazu 273 600 0000-0002-5068-2164 start=2019; end=2019 2025-02-14T13:23:55Z 2025-02-14T13:23:55Z 2024-05-03 http://hdl.handle.net/10259/10229 10.71486/sc0z-9x73 UV/Vis absorption spectroelectrochemistry is a very promising analytical technique due to the complementary information that is simultaneously obtained from electrochemistry and spectroscopy. In this work, this technique is used in a parallel configuration to study the oxidation of folic acid in alkaline medium. Herein, UV/Vis absorption spectroelectrochemistry has been used to detect both the oxidation products and the folic acid consumed at the electrode/solution interface, allowing us to develop an analytical protocol to quantify vitamin B9 in pharmaceutical tablets. Linear ranges of three orders of magnitude have been achieved in basic medium (pH = 12.9), obtaining high repeatability and low detection limits. The spectroelectrochemical determination of folic acid in pharmaceutical tablets at alkaline pH values is particularly interesting because of the changes that occur in the optical signal during the electrochemical oxidation of FA, providing results with very good figures of merit and demonstrating the utility and versatility of this hyphenated technique, UV/Vis absorption spectroelectrochemistry. Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Authors acknowledge the financial support from Ministerio de Economía y Competitividad (Grant CTQ2017-83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18), and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018-102412-T). F.O. is grateful for the contract funded by Junta de Castilla y León, the European Social Fund, and the Youth Employment Initiative. text/plain application/zip text/csv eng Universidad de Burgos http://hdl.handle.net/10259/6118 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-83935-R/ES/ESPECTROELECTROQUIMICA RAMAN CUANTITATIVA/ info:eu-repo/grantAgreement/Junta de Castilla y León//BU297P18//Fusión de técnicas espectroelectroquímicas avanzadas/ info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RED2018-102412-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS/ Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Vitamin B9 Pharmaceutical drug Electrochemistry UV/Vis absorption spectroscopy Química analítica Chemistry, Analytic Dataset of the work “UV Vis absorption spectroelectrochemistry of folic acid” dataset info:eu-repo/semantics/acceptedVersion 2024 LICENSE license.txt license.txt text/plain; charset=utf-8 999 https://riubu.ubu.es/bitstream/10259/10229/4/license.txt b295bcbce42e2caabeb0c623d3860c06 MD5 4 CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 908 https://riubu.ubu.es/bitstream/10259/10229/3/license_rdf 0175ea4a2d4caec4bbcc37e300941108 MD5 3 ORIGINAL readme.txt readme.txt text/plain 6277 https://riubu.ubu.es/bitstream/10259/10229/5/readme.txt f28f9c91c9f8c2553a64ddcc7c3beb80 MD5 5 Olmo-Dataset_UV_Vis_absorption_spectroelectrochemistry_of_folic_acid.zip Olmo-Dataset_UV_Vis_absorption_spectroelectrochemistry_of_folic_acid.zip application/zip 164567708 https://riubu.ubu.es/bitstream/10259/10229/7/Olmo-Dataset_UV_Vis_absorption_spectroelectrochemistry_of_folic_acid.zip 68ee9fe38efe7c0818b4bd8455a7bf50 MD5 7 10259/10229 oai:riubu.ubu.es:10259/10229 2025-06-04 14:54:32.994 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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