2026-04-22T15:07:01Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/105052025-05-29T00:05:14Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594

Gómez Gil, Sara Suárez Pantiga, Samuel Pedrosa Sáez, María de los Remedios Sanz Díez, Roberto 2025-05-28T07:16:54Z 2025-05-28T07:16:54Z 2024-10 1615-4150 http://hdl.handle.net/10259/10505 10.1002/adsc.202401170 1615-4169 A molybdenum-catalyzed synthesis of N-(hetero)aryl pyrroles directly from inexpensive and commonly available (hetero)nitroarenes via reduction with pinacol and annulation with 1,4-dicarbonyls or cyclobutane-1,2-diols has been described. The process does not require an inert atmosphere and tolerates the presence of air and water. This non-noble catalytic system shows high chemoselectivity, allowing a diverse range of potentially reducible functional groups such as alkynes, alkenes, halogens, cyano, and carbonyls. Moreover, this strategy enables the reuse of a waste byproduct as reactant, facilitating the formation of challenging 1,4-dicarbonyls from accessible cyclobutane-1,2-diols used as reducing agents. We acknowledge the financial support from Ministerio de Ciencia, Innovación y Universidades (PID2020-115789GB-C21/AEI/10.1039/501100011033 and PDC2021-115789GB-C21), and Junta de Castilla y León and FEDER (BU028P23). S.G.-G. thanks Ministerio de Ciencia, Innovación y Universidades for a FPU predoctoral contract. S.S.-P. thanks Ministerio de Ciencia, Innovación y Universidades and “NextGenerationEU”/PRTR EU for a Ramón y Cajal contract (RYC2021-031533-I). application/pdf eng Wiley Advanced Synthesis & Catalysis. 2024, V. 367, n. 4, p. e202401170 https://doi.org/10.1002/adsc.202401170 Atribución-NoComercial 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess Nitroarenes Pyrroles Reduction Molybdenum Glycols Química Química orgánica Chemistry Chemistry, Organic Molybdenum‐Catalyzed Direct Synthesis of Pyrroles from Nitroarenes with Glycols as Reductants info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Advanced Synthesis & Catalysis 367 4 e202401170