2026-04-22T15:07:38Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/105052025-05-29T00:05:14Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594
Gómez Gil, Sara
911
600
0000-0001-6556-5844
Suárez Pantiga, Samuel
544
600
0000-0002-4249-7807
Pedrosa Sáez, María de los Remedios
422
600
0000-0001-7083-8093
Sanz Díez, Roberto
531
600
0000-0003-2830-0892
2025-05-28T07:16:54Z
2025-05-28T07:16:54Z
2024-10
1615-4150
http://hdl.handle.net/10259/10505
10.1002/adsc.202401170
1615-4169
A molybdenum-catalyzed synthesis of N-(hetero)aryl pyrroles directly from inexpensive and commonly available (hetero)nitroarenes via reduction with pinacol and annulation with 1,4-dicarbonyls or cyclobutane-1,2-diols has been described. The process does not require an inert atmosphere and tolerates the presence of air and water. This non-noble catalytic system shows high chemoselectivity, allowing a diverse range of potentially reducible functional groups such as alkynes, alkenes, halogens, cyano, and carbonyls. Moreover, this strategy enables the reuse of a waste byproduct as reactant, facilitating the formation of challenging 1,4-dicarbonyls from accessible cyclobutane-1,2-diols used as reducing agents.
We acknowledge the financial support from Ministerio de Ciencia, Innovación y Universidades (PID2020-115789GB-C21/AEI/10.1039/501100011033 and PDC2021-115789GB-C21), and Junta de Castilla y León and FEDER (BU028P23). S.G.-G. thanks Ministerio de Ciencia, Innovación y Universidades for a FPU predoctoral contract. S.S.-P. thanks Ministerio de Ciencia, Innovación y Universidades and “NextGenerationEU”/PRTR EU for a Ramón y Cajal contract (RYC2021-031533-I).
application/pdf
eng
Wiley
Advanced Synthesis & Catalysis. 2024, V. 367, n. 4, p. e202401170
https://doi.org/10.1002/adsc.202401170
Atribución-NoComercial 4.0 Internacional
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
Nitroarenes
Pyrroles
Reduction
Molybdenum
Glycols
Química
Química orgánica
Chemistry
Chemistry, Organic
Molybdenum‐Catalyzed Direct Synthesis of Pyrroles from Nitroarenes with Glycols as Reductants
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Advanced Synthesis & Catalysis
367
4
e202401170
THUMBNAIL
Gómez-as&c_2024.pdf.jpg
Gómez-as&c_2024.pdf.jpg
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https://riubu.ubu.es/bitstream/10259/10505/4/G%c3%b3mez-as%26c_2024.pdf.jpg
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MD5
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LICENSE
license.txt
license.txt
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https://riubu.ubu.es/bitstream/10259/10505/3/license.txt
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ORIGINAL
Gómez-as&c_2024.pdf
Gómez-as&c_2024.pdf
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https://riubu.ubu.es/bitstream/10259/10505/1/G%c3%b3mez-as%26c_2024.pdf
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10259/10505
oai:riubu.ubu.es:10259/10505
2025-05-29 02:05:14.05
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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