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<title>Self-Reported Post-COVID Symptoms at 18 Months After Infection Among Adults in Southern Brazil: A Cross-Sectional Study</title>
<creator>Brito, Franciele Aline Machado de</creator>
<creator>Laranjeira, Carlos</creator>
<creator>Moroskoski, Márcia</creator>
<creator>Salci, Maria Aparecida</creator>
<creator>Rossoni, Stéfane Lele</creator>
<creator>Baccon, Wanessa Cristina</creator>
<creator>Oliveira, Rosana Rosseto de</creator>
<creator>Marques, Priscila Garcia</creator>
<creator>Góes, Herbert Leopoldo de Freitas</creator>
<creator>Mello, Fernanda Fontes</creator>
<creator>Blaszczak, Flávia Renata Baldissera da Cruz</creator>
<creator>Vissoci, João Ricardo Nickenig</creator>
<creator>Puente Alcaraz, Jesús</creator>
<creator>Facchini, Luiz Augusto</creator>
<creator>Carreira, Lígia</creator>
<subject>SARS-CoV-2</subject>
<subject>Long Covid</subject>
<subject>Signs and symptoms</subject>
<subject>Cross-sectional</subject>
<subject>Brazil</subject>
<description>Background/Objectives: Currently, there is a limited understanding of the long-term consequences following acute COVID-19, referred to as long COVID. This cross-sectional study aims to analyze the prevalence of persistent signs and symptoms of long COVID, 18 months after primary SARS-CoV-2 infection in adults in southern Brazil. Methods: Using two national databases (the digital registry of SARS-CoV-2 positive cases), 370 individuals living in the state of Paraná (Brazil) were recruited. Data were collected through telephone interviews conducted in 2021 and 2022. Results: The overall prevalence of long COVID was 66.2% among study participants. During the acute phase of infection, the most common symptom clusters included neurological symptoms (87.0%; n = 318), followed by respiratory (82.0%; n = 301), musculoskeletal (66.0%; n = 241), digestive (50.0%; n = 184), psychological (38.0%; n = 138), and endocrine symptoms (28.0%; n = 104). In the 18 month follow-up, the main persistent symptoms were memory loss (42.7%), fatigue (32.2%), anxiety (23.5%), dyspnea (19.7%), and hair loss (19.7%). The proportion of participants with long COVID was statistically higher in females (73.9%), those with a family income below two minimum wages (94.7%), those who do not practice physical activity (83.3%), those who report poor sleep quality (93.3%), those who use long-term medication (85.9%), those who needed health care in the previous six months (87.3%), those who required professional and/or family care (79.3%), those who were in the ICU (79.0%), and those who used ventilatory support (77.5%). Conclusions: Long COVID is a complex condition that requires long-term monitoring and investment in health services due to its high prevalence and the health consequences in the population.</description>
<date>2026-02-12</date>
<date>2026-02-12</date>
<date>2025-01</date>
<type>info:eu-repo/semantics/article</type>
<identifier>https://hdl.handle.net/10259/11364</identifier>
<identifier>10.3390/healthcare13030228</identifier>
<identifier>2227-9032</identifier>
<language>eng</language>
<relation>Healthcare. 2025, V. 13, n. 3, p. 228-243</relation>
<relation>https://doi.org/10.3390/healthcare13030228</relation>
<rights>http://creativecommons.org/licenses/by/4.0/</rights>
<rights>info:eu-repo/semantics/openAccess</rights>
<rights>Atribución 4.0 Internacional</rights>
<publisher>MDPI</publisher>
</thesis></metadata></record></GetRecord></OAI-PMH>