2026-05-08T10:44:51Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/114622026-03-03T01:05:52Zcom_10259_9476com_10259.4_106com_10259_2604col_10259_9477
Repositorio Institucional de la Universidad de Burgos
author
Escobedo-Monge, Marlene Fabiola
author
Barrado, Enrique
author
Parodi-Román, Joaquín
author
Escobedo Monge, María Antonieta
author
Torres-Hinojal, María
author
Marugán Miguelsanz, José Manuel
2026-03-02T10:00:05Z
2026-03-02T10:00:05Z
2021-10
2072-6643
https://hdl.handle.net/10259/11462
10.3390/NU13103578
2072-6643
Copper is an essential micronutrient for humans. A cross-sectional and comparative study was done to assess serum Cu levels and serum copper/zinc (Cu/Zn) ratio and its association with nutritional indicators in a series of children and adolescents with chronic diseases. Anthropometric, biochemical, dietary, body composition, and bone densitometry assessments were carried out. Serum Cu and Zn were measured by atomic absorption spectrophotometry. Seventy-eight patients (55% women) participated. The mean serum Cu in the entire series and by nutritional status through body mass index (BMI) was normal. Serum Cu decreased significantly with age and was meaningfully higher in children than in adolescents. The risk of finding altered Cu levels in children and men was higher than in adolescents and women, respectively. Twenty-two per cent of patients had abnormal serum copper levels, 13 had hypercupremia, and four had hypocupremia. The Cu/Zn ratio was greater than 1.00 for 87% of the patients, which is an indicator of an inflammatory state. All patients with hypozincemia and hypocupremia had deficient Zn intake, but only 65% of the patients with hypercupremia had dietary Zn deficiency. Consequently, the Cu/Zn ratio could indicate an inflammatory state and a high risk of zinc deficiency in this specific child population.
eng
Atribución 4.0 Internacional
Hypocupremia
Hypercupremia
Inflammatory response
Risk of zinc deficiency
Serum zinc/copper ratio
Copper and Copper/Zn Ratio in a Series of Children with Chronic Diseases: A Cross-Sectional Study
info:eu-repo/semantics/article
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URL
https://riubu.ubu.es/bitstream/10259/11462/1/Escobedo-nutrients_2021.pdf
File
MD5
39909034a64c007c6c50e8c5b27e3714
7712290
application/pdf
Escobedo-nutrients_2021.pdf