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<dc:title>Combined creatine and β-hydroxy-β-methylbutyrate supplementation with integral conditioning exercise enhances functional performance and metabolic health in physically active older adults: A randomized controlled crossover trial</dc:title>
<dc:creator>Ramos-Hernández, Rafael</dc:creator>
<dc:creator>Busto Vázquez, Natalia</dc:creator>
<dc:creator>Miguel Ortega, Alvaro</dc:creator>
<dc:creator>Martínez Ferrán, María</dc:creator>
<dc:creator>Santamaría Peláez, Mirian</dc:creator>
<dc:creator>Saiz Rodríguez, Miriam</dc:creator>
<dc:creator>Mielgo Ayuso, Juan</dc:creator>
<dc:subject>Creatine monohydrate</dc:subject>
<dc:subject>Β-hydroxy-β-methylbutyrate</dc:subject>
<dc:subject>Older adults</dc:subject>
<dc:subject>Multicomponent training</dc:subject>
<dc:subject>Functional mobility</dc:subject>
<dc:subject>Metabolism</dc:subject>
<dc:subject>Endothelial function</dc:subject>
<dc:description>Objective: to investigate the effects of six weeks of CRE + HMB supplementation integrated with a supervised multicomponent exercise program on functional performance, metabolic efficiency, and physiological health in older adults. Conclusions: six weeks of CRE + HMB supplementation integrated with supervised multicomponent training enhanced mobility, metabolic efficiency, and selected physiological outcomes in physically active older adults. This strategy represents a safe, feasible, and practical approach to sustain functional independence and metabolic health with aging.</dc:description>
<dc:date>2026-05-13T07:40:39Z</dc:date>
<dc:date>2026-05-13T07:40:39Z</dc:date>
<dc:date>2026-01</dc:date>
<dc:type>info:eu-repo/semantics/article</dc:type>
<dc:identifier>https://hdl.handle.net/10259/11612</dc:identifier>
<dc:identifier>10.1007/s40520-025-03312-0</dc:identifier>
<dc:identifier>1720-8319</dc:identifier>
<dc:language>eng</dc:language>
<dc:relation>Aging Clinical and Experimental Research. 2026, V. 38, n. 1, 44</dc:relation>
<dc:relation>https://doi.org/10.1007/s40520-025-03312-0</dc:relation>
<dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
<dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
<dc:rights>Atribución 4.0 Internacional</dc:rights>
<dc:publisher>Springer</dc:publisher>
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