2026-04-17T20:11:55Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/42592021-11-10T09:38:26Zcom_10259_4249com_10259_5086com_10259_2604col_10259_4250
Repositorio Institucional de la Universidad de Burgos
author
Oca Casado, Mª Leticia
author
Rubio Martínez, Laura
author
Sarabia Peinador, Luis Antonio
author
Ortiz Fernández, Mª Cruz
2016-10-21T08:30:21Z
2018-09-16T02:45:06Z
2016-09
0021-9673
http://hdl.handle.net/10259/4259
10.1016/j.chroma.2016.07.074
Determining plasticizers and other additives migrated from plastic materials becomes a hard task when these substances are already present in the laboratory environment. This work dealt with this drawback in the multiresidue determination of four plasticizers (2,6-di-tert-butyl-4-methyl-phenol (BHT), diisobutyl phthalate (DiBP), bis(2-ethylhexyl) adipate (DEHA) and diisononyl phthalate (DiNP)) and a UV stabilizer (benzophenone (BP)) by gas chromatography/mass spectrometry (GC/MS) using DiBP-d4 as internal standard. The ubiquity of DiBP by a non-constant leaching process in the laboratory was detected, which could not guarantee the achievement of a trustworthy quantification. To handle this, the assessment of the level of DiBP in solvent blanks having fixed the probabilities of false non-compliance (α) and false compliance (β) at 0.01 was performed. On the other hand, another special case was that of DiNP, in whose chromatogram finger peaks appear because of an array of possible C9 isomers. PARAFAC, used for the identification and quantification of all the substances, is a useful chemometric tool that enabled a more reliable determination of this analyte since no peak areas were considered but chromatographic and spectral loadings.
Since phthalates may migrate from rubber latex items, an evaluation of the existence of matrix effects on the determination of the five analytes was conducted prior to an extraction with hexane from a dummy for infants. As matrix effects were present, the quantification of the compounds under study was performed following the standard addition method using PARAFAC sample loadings as response variable. As a result, the presence of BHT was confirmed, being its concentration equal to 37.87 μg L−1. Calibrations based on PARAFAC yielded the following values for the decision limit (CCα): 1.16 μg L−1 for BHT, 1.34 μg L−1 for BP, 1.84 μg L−1 for DEHA and 51.42 μg L−1 for DiNP(for α = 0.05 and two replicates).
eng
Attribution-NonCommercial-NoDerivatives 4.0 International
Phthalates
Plasticizers
Benzophenone
PTV-GC/MS
PARAFAC
Finger peak
Dealing with the ubiquity of phthalates in the laboratory when determining plasticizers by gas chromatography/mass spectrometry and PARAFAC
info:eu-repo/semantics/article
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URL
https://riubu.ubu.es/bitstream/10259/4259/1/Oca-JCA_2016.pdf
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Oca-JCA_2016.pdf
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https://riubu.ubu.es/bitstream/10259/4259/6/Oca-JCA_2016.pdf.txt
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Oca-JCA_2016.pdf.txt