2026-05-28T18:25:11Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/42782022-04-29T12:02:48Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594
Álvarez Manuel, Estela
25
500
Nieto Faza, Olalla .
22ecaaeb-839e-4c87-89aa-1aff3dc73b53
500
Silva López, Carlos
0ee5b0c9-6148-4e20-8d10-a4196558fb1c
500
Fernández Rodríguez, Manuel A.
174
500
Sanz Díez, Roberto
531
500
2016-11-22T09:15:54Z
2016-11-22T09:15:54Z
2015-09
0947-6539
http://hdl.handle.net/10259/4278
A cascade reaction of indoles with propargylic diols
involving an unprecedented metal-free 1,2-indole migration onto an
alkyne is here described. DFT calculations support a mechanism
consisting in a concerted nucleophilic attack of the indole nucleus
with loss of water followed by the 1,2-migration and subsequent
Nazarov cyclization. This Brønsted acid-catalyzed protocol affords
indole-functionalized benzofulvene derivatives in high yields.
Junta de Castilla y León(BU237U13) and Ministerio de Economía y Competitividad (MINECO) and FEDER (CTQ2013-48937-C2-1P and 2-P)
application/pdf
eng
Wiley-VCH Verlag
Chemistry-a european journal. 2015, V. 21, n. 37, p. 12889–12893
http://dx.doi.org/10.1002/chem.201502174
benzofulvenes
Brønsted acid
catalysis
indolemigration
Nazarov cyclization
Chemistry, Organic
Química orgánica
Brønsted Acid-Catalyzed Cascade Reactions Involving 1,2-Indole Migration
info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
info:eu-repo/semantics/openAccess
THUMBNAIL
Álvarez-CEJ_2015.pdf.jpg
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ORIGINAL
Álvarez-CEJ_2015.pdf
Álvarez-CEJ_2015.pdf
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https://riubu.ubu.es/bitstream/10259/4278/1/%c3%81lvarez-CEJ_2015.pdf
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LICENSE
license.txt
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TEXT
Álvarez-CEJ_2015.pdf.txt
Álvarez-CEJ_2015.pdf.txt
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10259/4278
oai:riubu.ubu.es:10259/4278
2022-04-29 14:02:48.091
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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