2026-06-04T14:31:20Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/43592022-04-29T12:02:48Zcom_10259_4313com_10259_5086com_10259_2604com_10259_4365col_10259_4314col_10259_4366

Vallejos Calzada, Saúl 567 500 Estévez Bolívar, Pedro Antonio 166 500 Ibeas Cortes, Saturnino 293 500 García García, Félix Clemente 201 500 Serna Arenas, Felipe 535 500 García Pérez, José Miguel 213 500 2017-03-14T09:48:16Z 2017-03-14T09:48:16Z 2012-03 1424-8220 http://hdl.handle.net/10259/4359 10.3390/s120302969 The preparation of a fluorogenic sensory material for the detection of biomolecules is described. Strategic functionalisation and copolymerisation of a water insoluble organic sensory molecule with hydrophilic comonomers yielded a crosslinked, water-swellable, easy-to-manipulate solid system for water ‘‘dip-in’’ fluorogenic coenzyme A, cysteine, and glutathione detection by means of host-guest interactions. The sensory material was a membrane with gel-like behaviour, which exhibits a change in fluorescence behaviour upon swelling with a water solution of the target molecules. The membrane follows a “turn-on” pattern, which permits the titration of the abovementioned biomolecules. In this way, the water insoluble sensing motif can be exploited in aqueous media. The sensory motif within the membrane is a chemically anchored piperazinedione-derivative with a weakly bound Hg(II). The response is caused by the displacement of the cation from the membrane due to a stronger complexation with the biomolecules, thus releasing the fluorescent sensory moieties within the membrane Spanish Ministerio de Ciencia e Innovación—Feder (MAT2011-22544) and by the Junta de Castilla y León (BU001A10-2) application/pdf eng MDPI Sensors, 2012, V. 12, n. 3, p. 2969-2982 http://dx.doi.org/10.3390/s120302969 Attribution 3.0 Unported http://creativecommons.org/licenses/by/3.0/ info:eu-repo/semantics/openAccess sensory materials chemosensor fluorogenic sensor biomolecules sensing biomolecules Chemistry Química An Organic/Inorganic Hybrid Membrane as a Solid “Turn-On” Fluorescent Chemosensor for Coenzyme A (CoA), Cysteine (Cys), and Glutathione (GSH) in Aqueous Media info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 908 https://riubu.ubu.es/bitstream/10259/4359/8/license_rdf f9a6a4096bf314846151c97900b2090d MD5 8 THUMBNAIL Vallejos-Sensors_2012.pdf.jpg Vallejos-Sensors_2012.pdf.jpg IM Thumbnail image/jpeg 4628 https://riubu.ubu.es/bitstream/10259/4359/7/Vallejos-Sensors_2012.pdf.jpg 52775f84ba3efe087899ec529a9ba83b MD5 7 ORIGINAL Vallejos-Sensors_2012.pdf Vallejos-Sensors_2012.pdf application/pdf 587433 https://riubu.ubu.es/bitstream/10259/4359/1/Vallejos-Sensors_2012.pdf 2a268b4fef7f5c17fb8596e5dcde0d4b MD5 1 LICENSE license.txt license.txt text/plain; charset=utf-8 998 https://riubu.ubu.es/bitstream/10259/4359/5/license.txt aa90105e1c90a1b4fe810649aa967b7d MD5 5 TEXT Vallejos-Sensors_2012.pdf.txt Vallejos-Sensors_2012.pdf.txt Extracted text text/plain 37172 https://riubu.ubu.es/bitstream/10259/4359/6/Vallejos-Sensors_2012.pdf.txt b08adce95daa94bb1d1b4ab168489133 MD5 6 10259/4359 oai:riubu.ubu.es:10259/4359 2022-04-29 14:02:48.491 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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