2026-05-05T05:39:34Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/43612022-12-19T13:18:42Zcom_10259_4354com_10259_5086com_10259_2604com_10259_4363com_10259_4365col_10259_4355col_10259_4364col_10259_4366

Díaz de Greñu Puertas, Borja 145 600 García Calvo, José 198 500 0000-0002-1873-0293 Cuevas Vicario, José Vicente 137 500 0000-0002-2421-1529 García Herbosa, Gabriel 205 500 0000-0002-2863-1272 García Ruiz, Begoña 217 500 0000-0002-0817-1651 Busto Vázquez, Natalia 83 500 0000-0001-9637-1209 Ibeas Cortes, Saturnino 293 500 0000-0003-1831-5943 Torroba Pérez, Tomás 554 500 0000-0002-5018-4173 Torroba, Blanca 3e544443-263b-43f9-95ed-8c9c0e9fb2f8 500 Herrera, Antonio 15276b20-904f-4f86-87f0-a29db3440401 500 Pons, Sebastian 6f546f46-3631-4278-b615-7a3d2e2809c7 500 2017-03-14T11:36:48Z 2017-03-14T11:36:48Z 2015-07 http://hdl.handle.net/10259/4361 Selected new fluorogenic probes that interact in different ways with Hg2+ and MeHg+ have been prepared and used for the chemical speciation of both cations in aqueous solution as well as in HEK293 cells. The best selective speciation of Hg2+ and MeHg+ has been achieved by in vitro approaches based on fluorogenic probes supported in cultured cells, due to the particular sensitivity of the HEK293 cells to permeation by Hg2+, MeHg+ and the fluorogenic probes. In particular, MeHg+ was selectively detected in cell nuclei by probe JG45. the Ministerio de Econom´ıa y Competitividad, Spain (Projects CTQ2012- 31611 and CTQ2014-58812-C2-2-R), Junta de Castilla y Le´on, Consejer´ıa de Educaci´on y Cultura y Fondo Social Europeo (Project BU246A12-1), Obra Social “la Caixa” OSLC-2012-007 and the European Commission, Seventh Framework Programme (Project SNIFFER FP7-SEC-2012-312411). application/pdf eng Royal Society of Chemistry Chemical Science. 2015, V. 6, n. 7, p. 3757-3764 http://dx.doi.org/10.1039/C5SC00718F info:eu-repo/grantAgreement/EC/FP7/312411 Attribution 3.0 Unported http://creativecommons.org/licenses/by/3.0/ info:eu-repo/semantics/openAccess Chemistry, Organic Química orgánica Chemical speciation of MeHg+ and Hg2+ in aqueous solution and HEK cells nuclei by means of DNA interacting fluorogenic probes info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 908 https://riubu.ubu.es/bitstream/10259/4361/8/license_rdf f9a6a4096bf314846151c97900b2090d MD5 8 THUMBNAIL Díaz-CHS_2015.pdf.jpg Díaz-CHS_2015.pdf.jpg IM Thumbnail image/jpeg 5016 https://riubu.ubu.es/bitstream/10259/4361/7/D%c3%adaz-CHS_2015.pdf.jpg b6e81aaff879dbf42e723d01c6020d63 MD5 7 ORIGINAL Díaz-CHS_2015.pdf Díaz-CHS_2015.pdf application/pdf 3528368 https://riubu.ubu.es/bitstream/10259/4361/1/D%c3%adaz-CHS_2015.pdf 7b79a32be8fd0d3e7100fe35bde5a6c0 MD5 1 LICENSE license.txt license.txt text/plain; charset=utf-8 999 https://riubu.ubu.es/bitstream/10259/4361/5/license.txt b295bcbce42e2caabeb0c623d3860c06 MD5 5 TEXT Díaz-CHS_2015.pdf.txt Díaz-CHS_2015.pdf.txt Extracted text text/plain 39602 https://riubu.ubu.es/bitstream/10259/4361/6/D%c3%adaz-CHS_2015.pdf.txt dda0767c27d520a15c4bbf30aefc8964 MD5 6 10259/4361 oai:riubu.ubu.es:10259/4361 2022-12-19 14:18:42.816 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es RWwgYXV0b3IgY29tbyDDum5pY28gdGl0dWxhciBkZSBsb3MgZGVyZWNob3MgZGUgcHJvcGllZGFkIGludGVsZWN0dWFsIGRlIGxhIG9icmEsIG8gZGlzcG9uaWVuZG8gZGUgbG9zIGRlYmlkb3MgcGVybWlzb3MgZGUgbG9zIG90cm9zIHRpdHVsYXJlcywgc2kgbG9zIGh1YmllcmEsIHkgZW4gdmlydHVkIGRlIGxvcyBkZXJlY2hvcyBxdWUgbGUgY29uZmllcmUgbGEgbGVnaXNsYWNpw7NuIHZpZ2VudGUgc29icmUgcHJvcGllZGFkIGludGVsZWN0dWFsIHkgZGVyZWNob3MgZGUgYXV0b3IsIA0KQVVUT1JJWkEgYSBsYSBVbml2ZXJzaWRhZCBkZSBCdXJnb3MgYSBkaWZ1bmRpciwgZGUgbWFuZXJhIGdyYXR1aXRhLCBlbCBjb250ZW5pZG8gZGUgbG9zIGFyY2hpdm9zIGRpZ2l0YWxlcyBxdWUgY29ycmVzcG9uZGVuIGFsIGRvY3VtZW50byBkZXNjcml0byBhbnRlcmlvcm1lbnRlLCBjb24gY2Fyw6FjdGVyIG5vIGV4Y2x1c2l2byB5IGRlIG1hbmVyYSBww7pibGljYSBlbiBhY2Nlc28gYWJpZXJ0byBhIHRyYXbDqXMgZGUgSW50ZXJuZXQsIHBhcmEgbG8gcXVlIGxhIEJpYmxpb3RlY2EgcHJvY2VkZXLDoSBhIGFyY2hpdmFybG9zIGVuIGVsIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwuIEFzaW1pc21vIGF1dG9yaXphIGEgbGEgVW5pdmVyc2lkYWQgZGUgQnVyZ29zIGEgcmVhbGl6YXIgbGFzIHRyYW5zZm9ybWFjaW9uZXMgbmVjZXNhcmlhcyBkZSBmb3JtYXRvLCBubyBkZSBjb250ZW5pZG8sIHBhcmEgZ2FyYW50aXphciBsYSBwcmVzZXJ2YWNpw7NuIHkgZWwgYWNjZXNvIGVuIGVsIGZ1dHVyby4NCg0KRWwgYXV0b3IgZGlzcG9uZSwgZW4gdG9kbyBjYXNvLCBkZWwgZGVyZWNobyBhIHJldm9jYXIgZXN0YSBhdXRvcml6YWNpw7NuLg0KDQpMYSBjZXNpw7NuIGRlIGRlcmVjaG9zIGRlIGVzdGEgb2JyYSBzZSBlbmN1ZW50cmEgc3VqZXRhIGEgbGEgbGVnaXNsYWNpw7NuIHZpZ2VudGUgc29icmUgcHJvcGllZGFkIGludGVsZWN0dWFsIHkgZGVyZWNob3MgZGUgYXV0b3Iu