2026-05-23T19:27:48Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/43982022-04-29T12:02:47Zcom_10259_4862com_10259_5086com_10259_2604col_10259_4863

Fernández Natal, Isabel e36a25a1-d470-4ce6-bbf1-d2b47990abd3 500 Rodríguez Lázaro, David 478 500 Marrodán Ciordia, T. 476c8b98-006b-4bc4-a562-9c579b56feba 500 Sáez Nieto, J. A. d614fb16-fd73-4429-b084-6f523f09aa56 500 Valdezate Ramos, S. 3ad3693c-50c0-42ff-bef0-e5e9f33194a2 500 Rodríguez Pollán, R. H. ab5dc450-834d-4c35-b7ce-82d9f016b36e 500 Tauch, A. 141c4ffc-93fc-4e35-9b2b-ea8ee6ca16c2 500 Soriano, F. 4a376180-9f85-4972-9f72-657c99f3f90c 500 2017-03-30T11:34:29Z 2017-03-30T11:34:29Z 2016-11 http://hdl.handle.net/10259/4398 Human infections associated with Corynebacterium kroppenstedtii are rarely reported, and this organism is usually described as antibiotic sensitive. Almost all published cases of C. kroppenstedtii infections have been associated with breast pathology in women and have been described in New Zealand, France, Canada, India and Japan. Here we describe the microbiologic characteristics of two strains isolated from two women diagnosed of granulomatous mastitis in Spain. One C. kroppenstedtii isolate was antibiotic sensitive while the other was multidrug resistant. Biochemical identification was possible using a wide battery of methods including API Coryne V2.0, API Strep, API NH, API NE, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene amplification and sequencing. Antimicrobial susceptibility to 28 antibiotics as determined by Etest showed one isolate being sensitive to benzylpenicillin, ciprofloxacin, moxifloxacin, gentamicin, vancomycin, clindamycin, tetracycline, linezolid and rifampin. The second isolate showed resistance to ciprofloxacin, moxifloxacin, clindamycin, tetracycline and rifampin. The multidrug-resistant isolate contained the erm(X), tet(W), cmx, aphA1-IAB, strAB and sul1 resistance genes known from the R plasmid pJA144188 of Corynebacterium resistens. These genes were absent in the genome of the antibiotic-sensitive isolate. This report confirms the tropism of this microorganism for women's breasts and presents the first description of a multidrug-resistant C. kroppenstedtii strain. Gerencia Regional de Salud, Junta de Castilla y León, Spain, research project GRS 698/A/2011 application/pdf eng Elsevier New Microbes and New Infections. 2016, V. 14, p. 93–97 http://dx.doi.org/10.1016/j.nmni.2016.09.006 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Antimicrobial susceptibility Corynebacterium kroppenstedtii granulomatous mastitis MALDI-TOF MS multidrug-resistant isolate Microbiology Microbiología Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 805 https://riubu.ubu.es/bitstream/10259/4398/8/license_rdf 4460e5956bc1d1639be9ae6146a50347 MD5 8 THUMBNAIL Fernández-NMNI_2016.pdf.jpg Fernández-NMNI_2016.pdf.jpg IM Thumbnail image/jpeg 4789 https://riubu.ubu.es/bitstream/10259/4398/7/Fern%c3%a1ndez-NMNI_2016.pdf.jpg 286751ba4fb72a0d00b39bf4273e0661 MD5 7 ORIGINAL Fernández-NMNI_2016.pdf Fernández-NMNI_2016.pdf application/pdf 68314 https://riubu.ubu.es/bitstream/10259/4398/1/Fern%c3%a1ndez-NMNI_2016.pdf 9540deb088e4a7385c426226738a7014 MD5 1 LICENSE license.txt license.txt text/plain; charset=utf-8 999 https://riubu.ubu.es/bitstream/10259/4398/5/license.txt b295bcbce42e2caabeb0c623d3860c06 MD5 5 TEXT Fernández-NMNI_2016.pdf.txt Fernández-NMNI_2016.pdf.txt Extracted text text/plain 23674 https://riubu.ubu.es/bitstream/10259/4398/6/Fern%c3%a1ndez-NMNI_2016.pdf.txt e682430fd4400bbd069fd9906b3b5a16 MD5 6 10259/4398 oai:riubu.ubu.es:10259/4398 2022-04-29 14:02:47.852 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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