2026-04-29T01:33:55Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/44362022-04-29T12:02:48Zcom_10259_4313com_10259_5086com_10259_2604col_10259_4314

Morro, Ana 30f3f291-90aa-40a4-a800-efdbefd3276e 500 Abrusci, Concepción 08706e09-8f65-4e77-9974-9814f5b59e95 500 Pablos, Jesús Luis ace6696a-c30a-409d-a4ce-1f48eda8f1ab 500 Marín, Irma bed1ba53-a6cd-408b-aa2e-dcb25352c1a1 500 García García, Félix Clemente 201 500 García Pérez, José Miguel 213 500 2017-04-28T09:26:17Z 2019-06-01T02:45:06Z 2017-06 http://hdl.handle.net/10259/4436 Microbial colonisation of synthetic materials is a great concern in many fields, e.g., in implant surgery and medical devices; therefore biocompatible hydrophilic organic materials with inherent antimicrobial properties are of current research interest. In this work, we describe the preparation of antibacterial and biocompatible polymeric film based on N-vinyl-2-pyrrolidone (VP) and 2-hydroxyethyl acrylate (HEA), using ethyleneglycol dimethacrylate (EGDMA), and synthetic acrylic monomer containing sulfadiazine chemically anchored. The synthesised polyvinylpyrrolidone (PVP)-based films were characterized by different techniques (1H and 13C NMR, ATR-FTIR, SEM, and TGA). In this study, the biophysical responses of bacteria and L929 cells towards the prepared materials as model device surfaces were evaluated. The membrane that contains the anchored sulfadiazine moiety showed excellent antibacterial activity against Escherichia coli as well as good biocompatibility. Based on the experimental results, this material is a good candidate for medical applications as a biomaterial. Spanish Ministerio de Economía y Competitividad-Feder (MAT2014-54137-R and MAT2012-31709) and by the Consejería de Educación – Junta de Castilla y León – Feder (BU061U16) application/pdf eng Elsevier European Polymer Journal. 2017, V. 91, p. 274–282 https://doi.org/10.1016/j.eurpolymj.2017.04.012 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess PVP Sulfadiazine Antibacterial polymer Biocompatible Chemistry Química Inherent antibacterial activity and in vitro biocompatibility of hydrophilic polymer film containing chemically anchored sulfadiazine moieties info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 805 https://riubu.ubu.es/bitstream/10259/4436/8/license_rdf 4460e5956bc1d1639be9ae6146a50347 MD5 8 THUMBNAIL Morro-EPJ_2017.pdf.jpg Morro-EPJ_2017.pdf.jpg IM Thumbnail image/jpeg 4475 https://riubu.ubu.es/bitstream/10259/4436/7/Morro-EPJ_2017.pdf.jpg 146d0ec1982000e670a3ebe50a28bdea MD5 7 ORIGINAL Morro-EPJ_2017.pdf Morro-EPJ_2017.pdf application/pdf 931211 https://riubu.ubu.es/bitstream/10259/4436/1/Morro-EPJ_2017.pdf 2366848b243f6e3497d2b73b084409cc MD5 1 LICENSE license.txt license.txt text/plain; charset=utf-8 998 https://riubu.ubu.es/bitstream/10259/4436/5/license.txt aa90105e1c90a1b4fe810649aa967b7d MD5 5 TEXT Morro-EPJ_2017.pdf.txt Morro-EPJ_2017.pdf.txt Extracted text text/plain 35535 https://riubu.ubu.es/bitstream/10259/4436/6/Morro-EPJ_2017.pdf.txt 5f978d43c70678402ad4ffb211213c06 MD5 6 10259/4436 oai:riubu.ubu.es:10259/4436 2022-04-29 14:02:48.502 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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