2026-04-29T04:01:09Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/47682024-07-24T11:37:00Zcom_10259_9476com_10259.4_106com_10259_2604col_10259_9477
Valle Orero, J.
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Wildes, Andew R.
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Theodorakopoulos, Nikos
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Cuesta López, Santiago
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0000-0002-7401-3889
Garden, J. L. .
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500
Danilkin, S. .
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Peyrard, Michel
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2018-03-23T10:29:58Z
2018-03-23T10:29:58Z
2014-11
1367-2630
http://hdl.handle.net/10259/4768
10.1088/1367-2630/16/11/113017
The DNA molecule can take various conformational forms. Investigations
focus mainly on the so-called ‘B-form’, schematically drawn in the famous
paper by Watson and Crick [1]. This is the usual form of DNA in a biological
environment and is the only form that is stable in an aqueous environment.
Other forms, however, can teach us much about DNA. They have the same
nucleotide base pairs for ‘building blocks’ as B-DNA, but with different
relative positions, and studying these forms gives insight into the interactions
between elements under conditions far from equilibrium in the B-form.
Studying the thermal denaturation is particularly interesting because it provides
a direct probe of those interactions which control the growth of the
fluctuations when the ‘melting’ temperature is approached. Here we report
such a study on the ‘A-form’ using calorimetry and neutron scattering. We
show that it can be carried further than a similar study on B-DNA, requiring
the improvement of thermodynamic models for DNA.
application/pdf
eng
IOP Publising
New Journal of Physics, 2014, V. 16, November 2014
https://doi.org/10.1088/1367-2630/16/11/113017
Attribution 3.0 Unported
https://creativecommons.org/licenses/by/3.0/
info:eu-repo/semantics/openAccess
Física
Physics
Thermal denaturation of A-DNA
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
CC-LICENSE
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10259/4768
oai:riubu.ubu.es:10259/4768
2024-07-24 13:37:00.493
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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