2026-04-20T05:46:36Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/48152022-04-29T12:02:46Zcom_10259_4313com_10259_5086com_10259_2604com_10259_3924col_10259_4314col_10259_3925

Vallejos Calzada, Saúl Hernando Santa Cruz, Elsa Trigo López, Miriam García García, Félix Clemente García Valverde, María Iturbe, David . Cabero, María Jesús . Quesada Pato, Roberto García Pérez, José Miguel 2018-06-19T08:23:24Z 2019-06-14T02:45:07Z 2018-06 2050-750X http://hdl.handle.net/10259/4815 10.1039/c8tb00682b We have developed a new extremely hydrophilic polymeric film suitable for the detection and quantification of chloride in human sweat directly on the skin. The film, or membrane, has chemically anchored 6-methoxyquinoline groups as chloride responsive fluorescent motifs. We have prepared the sensory material from a standard vinyl copolymer, by a convenient and easy solid-phase reaction. The sensory material has a water swelling percentage of 700%, facilitating an immediate detection of chloride, is reusable for at least 6 cycles and can be handled without care by unskilled persons. The initially high fluorescence of the material decreases in the presence of chloride, allowing the quantification of chloride concentration by using the colour definition of a digital picture or a fluorimeter. The suitability of the material to perform quantitative chloride analysis of human sweat by putting it in contact with the skin offers promise for its application in the sweat test used for the diagnosis of cystic fibrosis (CF). FEDER and both the Spanish Ministerio de Economía y Competitividad (MAT2014-54137-R and MAT2017-84501-R) and the Consejería de Educación – Junta de Castilla y León (BU092U16 and BU061U16) application/pdf eng Royal Society of Chemistry Journal of Materials Chemistry B. 2016, V. 6, n. 22, p. 3735-3741 https://doi.org/10.1039/c8tb00682b info:eu-repo/grantAgreement/MINECO/MAT2014-54137-R info:eu-repo/grantAgreement/MINECO/MAT2017-84501-R info:eu-repo/grantAgreement/JCyL/BU092U16 info:eu-repo/grantAgreement/JCyL/BU061U16 Chemistry, Organic Química orgánica Polymeric chemosensor for the detection and quantification of chloride in human sweat. Application to the diagnosis of cystic fibrosis info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion info:eu-repo/semantics/openAccess