2026-06-30T01:14:50Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/49242021-11-10T09:38:25Zcom_10259_3593com_10259_5086com_10259_2604com_10259_3596col_10259_3594col_10259_3597
Repositorio Institucional de la Universidad de Burgos
author
Rubio Presa, Rubén
author
Pedrosa Sáez, María de los Remedios
author
Fernández Rodríguez, Manuel A.
author
Arnáiz García, Francisco Javier
author
Sanz Díez, Roberto
2018-09-07T10:20:10Z
2018-10-06T02:45:06Z
2017-10
1523-7060
http://hdl.handle.net/10259/4924
10.1021/acs.orglett.7b02792
A novel domino reduction/imine formation/intramolecular cyclization/oxidation for the efficient synthesis of pyrrolo(indolo)[1,2-a]quinoxalines and pyrrolo(indolo)[3,2-c]-quinolines from readily available nitrobenzenes and glycols is reported. The process utilizes the carbonyl byproduct of the initial dioxomolybdenum(VI)-catalyzed reduction of nitroaromatics with glycols as a reagent for the imine generation. This method represents the first sustainable domino reaction for the preparation of biologically relevant heterocycles that internally incorporates the waste formed in the first step to the final product.
eng
Molybdenum-Catalyzed Synthesis of Nitrogenated Polyheterocycles from Nitroarenes and Glycols with Reuse of Waste Reduction By-product
info:eu-repo/semantics/article
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URL
https://riubu.ubu.es/bitstream/10259/4924/1/Rubio-ol_2017.pdf
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URL
https://riubu.ubu.es/bitstream/10259/4924/3/Rubio-ol_2017.pdf.txt
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text/plain
Rubio-ol_2017.pdf.txt