2026-06-29T23:00:38Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/52422021-11-02T12:06:21Zcom_10259_4725com_10259_5086com_10259_2604col_10259_4726
Repositorio Institucional de la Universidad de Burgos
author
Perdomo Hernández, Germán M.
author
Merino, Beatriz
author
Fernández Díaz, Cristina M. .
author
Cózar Castellano, Irene
2020-03-13T09:13:36Z
2020-03-13T09:13:36Z
2020-01
http://hdl.handle.net/10259/5242
10.3390/nu12010094
2072-6643
The worldwide epidemics of obesity and diabetes have been linked to increased sugar consumption in humans. Here, we review fructose and glucose metabolism, as well as potential molecular mechanisms by which excessive sugar consumption is associated to metabolic diseases and insulin resistance in humans. To this end, we focus on understanding molecular and cellular mechanisms of fructose and glucose transport and sensing in the intestine, the intracellular signaling effects of dietary sugar metabolism, and its impact on glucose homeostasis in health and disease. Finally, the peripheral and central effects of dietary sugars on the gut–brain axis will be reviewed.
eng
Atribución 4.0 Internacional
fructose
glucose
small intestine
liver
brain
gut-brain axis
non-alcoholic fatty liver
insulin resistance
metabolic syndrome
type 2 diabetes mellitus
Intestinal fructose and glucose metabolism in health and disease
info:eu-repo/semantics/article
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URL
https://riubu.ubu.es/bitstream/10259/5242/1/Merino-nutrients_2020.pdf
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Merino-nutrients_2020.pdf
URL
https://riubu.ubu.es/bitstream/10259/5242/5/Merino-nutrients_2020.pdf.txt
File
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text/plain
Merino-nutrients_2020.pdf.txt