2026-05-14T06:33:53Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/53342022-12-20T10:31:59Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

Garoz Ruiz, Jesús 226 500 0000-0002-5775-4247 Guillen Posteguillo, Carlos 268 600 Colina Santamaría, Álvaro 122 500 0000-0003-0339-356X Heras Vidaurre, Aránzazu 273 500 0000-0002-5068-2164 2020-06-10T09:14:35Z 2020-06-10T09:14:35Z 2019-04 0039-9140 http://hdl.handle.net/10259/5334 10.1016/j.talanta.2018.12.002 The amount of qualitative and quantitative information provided by a UV–vis absorption spectroelectrochemistry (SEC) experiment is sometimes wasted. However, almost all electrochemical and spectroscopic data can provide valuable information. In this spirit, the main objective proposed in this work is the quantitative resolution of catechol/dopamine (CAT/DA) and dopamine/epinephrine (DA/EP) mixtures, using spectroelectrochemical sensors in long optical path length arrangement based on bare optical fibers in parallel configuration with respect to carbon nanotubes or screen-printed electrodes. These compounds show extremely similar electrochemical and spectroscopic responses at high acidic pH, being impossible to determine their concentrations in the mixtures just using univariate regression models. To our knowledge, the SEC ability to resolve complex mixtures has never been demonstrated before with signals with this degree of overlapping. The quantitative analysis of these mixtures is possible using multivariate regression analysis of a set of time-resolved spectroelectrochemical data with a powerful statistical tool such as parallel factor analysis (PARAFAC). PARAFAC enables us to extract all the information from the experiments, allowing us to quantify the different analytes in mixtures of varying concentrations with excellent results. This milestone for spectroelectroanalysis illustrates the expected capabilities of SEC and demonstrates experimentally the potential of this technique for sensing of biomolecules. Ministerio de Economía y Competitividad (CTQ2014-55583-R; CTQ2014-61914-EXP; CTQ2015-71955-REDT; CTQ2017-83935-R AEI/FEDER, UE) and Junta de Castilla y León (BU033-U16) is gratefully acknowledged. Jesus Garoz- Ruiz thanks Ministerio de Educación, Cultura y Deporte for his FPU fellowship (FPU12/02795) and Ministerio de Economía y Competitividad for his postdoctoral contracts (CTQ2014-55583-R; CTQ2017-83935-R AEI/FEDER, UE). application/pdf eng Elsevier Talanta. 2019, V. 195, p. 815-821 https://doi.org/10.1016/j.talanta.2018.12.002 info:eu-repo/grantAgreement/MINECO/CTQ2014-55583-R info:eu-repo/grantAgreement/MINECO/CTQ2014-61914-EXP info:eu-repo/grantAgreement/MINECO/CTQ2015-71955-REDT info:eu-repo/grantAgreement/MINECO/CTQ2017-83935-R info:eu-repo/grantAgreement/JCyL/BU033-U16 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Spectroelectrochemistry Carbon nanotubes Screen-printed electrodes Optical fibers Dopamine Epinephrine Química analítica Chemistry, Analytic Application of spectroelectroanalysis for the quantitative determination of mixtures of compounds with highly overlapping signals info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Talanta 195 815 821 TEXT Garoz-talanta_2019.pdf.txt Garoz-talanta_2019.pdf.txt Extracted text text/plain 47401 https://riubu.ubu.es/bitstream/10259/5334/5/Garoz-talanta_2019.pdf.txt aa38855aaccecd179271f668dc5ed7ac MD5 5 THUMBNAIL Garoz-talanta_2019.pdf.jpg Garoz-talanta_2019.pdf.jpg IM Thumbnail image/jpeg 4224 https://riubu.ubu.es/bitstream/10259/5334/4/Garoz-talanta_2019.pdf.jpg 89855418270f24a1fdb4adb8d82e64ea MD5 4 LICENSE license.txt license.txt text/plain; charset=utf-8 999 https://riubu.ubu.es/bitstream/10259/5334/3/license.txt b295bcbce42e2caabeb0c623d3860c06 MD5 3 CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 805 https://riubu.ubu.es/bitstream/10259/5334/2/license_rdf 4460e5956bc1d1639be9ae6146a50347 MD5 2 ORIGINAL Garoz-talanta_2019.pdf Garoz-talanta_2019.pdf application/pdf 990594 https://riubu.ubu.es/bitstream/10259/5334/1/Garoz-talanta_2019.pdf 58fe7e92da28617bd7b40af5b125c366 MD5 1 10259/5334 oai:riubu.ubu.es:10259/5334 2022-12-20 11:31:59.189 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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