2026-05-11T16:27:22Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/53362022-04-08T07:44:09Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

Determination of uric acid in synthetic urine by using electrochemical surface oxidation enhanced Raman scattering Hernández Muñoz, Sheila Perales Rondon, Juan Víctor Heras Vidaurre, Aránzazu Colina Santamaría, Álvaro Spectroelectrochemistry Electrochemistry Raman EC-SOERS Química analítica Chemistry, Analytic In this work, a new and easy methodology to determine uric acid in relevant samples using Raman spectroelectrochemistry is presented. The spectroelectrochemistry experiment is based on the in-situ formation of a suitable substrate that enables the enhancement of the Raman signal of an analyte during the oxidation stage of a silver electrode. This phenomenon is known as electrochemical surface oxidation enhanced Raman scattering (EC-SOERS) and has proved to be useful in quantitative analysis using disposable screen printed electrodes. The successful combination of EC-SOERS with PARAFAC analysis allows the determination of uric acid in a relevant complex sample avoiding the use of standard addition method and without using a baseline correction, which simplifies the application of such methodology in routine analysis. Ministerio de Economía y Competitividad (Grants CTQ2017-83935-R-AEI/FEDERUE) and Junta de Castilla y León (Grant BU297P18) 2020-06-10T09:51:43Z 2020-06-10T09:51:43Z 2019-11 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion 0003-2670 http://hdl.handle.net/10259/5336 10.1016/j.aca.2019.07.057 eng Analytica Chimica Acta. 2019, V. 1085, p. 61-67 https://doi.org/10.1016/j.aca.2019.07.057 info:eu-repo/grantAgreement/MINECO/CTQ2017-83935-R info:eu-repo/grantAgreement/JCyL/BU297P18 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess application/pdf Elsevier