2026-04-27T21:51:01Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/53672021-11-02T12:02:52Zcom_10259_5363com_10259_5086com_10259_2604col_10259_5364

Osés Gómez, Sandra María 408 500 Marcos, Patricia d0c75ea2-41c8-478e-a177-5eb22497f252 500 Azofra, Patricia 5886e89f-a237-413d-8e16-1014749a6f87 500 Pablo, Ana de c0214733-3f65-4b2a-a811-23f8e4c48a8b 500 Fernández Muiño, Miguel Ángel 173 500 Sancho Ortiz, María Teresa 520 500 2020-07-02T10:31:26Z 2020-07-02T10:31:26Z 2020-01 http://hdl.handle.net/10259/5367 10.3390/antiox9010075 2076-3921 Propolis is a resinous vegetal exudate modified by bees, and is interesting as a preservative and potentially functional product. This work dealt with studying the common phenolic profiles and antioxidant capacities of 13 bee propolis from different geographical areas. Both hyaluronidase and angiotensin converting enzyme (ACE) inhibitory activities were also assessed and related when possible with particular phenolic compounds. High performance liquid chromatography‐ultraviolet detection (HPLC‐UV) analysis showed that every propolis contained p‐coumaric acid (1.2–12.2 mg/g) and ferulic acid (0.3–11.0 mg/g). Pinocembrin, catechin, and caffeic acid phenethyl ester (CAPE) plus galangin were the main flavonoids. Antioxidant activities were higher than 280 μmol trolox/g for trolox equivalent antioxidant capacity (TEAC), 0.099 mmol uric acid/g for radical‐scavenging effect on hydroxyl radicals, and 0.19 mg/mL for half maximal inhibitory concentration (IC50) of antioxidant activity against superoxide anion radical. Working with solutions of 10 mg/mL propolis, hyaluronidase inhibitory activity ranged between 0% and 68.20%, being correlated to ferulic acid content. ACE inhibitory effect determined by HPLC was higher than 78%, being correlated with catechin and p‐coumaric acid. Therefore, propolis could be useful for food, pharmaceutical, and cosmetic companies, also helping to reduce risk factors for diseases related to oxidative damage, inflammatory processes, and hypertension. This research also highlights the necessity for harmonized analysis methods and the expression of results for propolis. application/pdf eng MDPI Antioxidants. 2020, V. 9, n. 1, 75 https://doi.org/10.3390/antiox9010075 Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess propolis phenolic profile antioxidant capacities hyaluronidase inhibitory activity ACE inhibitory activity Alimentos Food Phenolic Profile, Antioxidant Capacities and Enzymatic Inhibitory Activities of Propolis from Different Geographical Areas: Needs for Analytical Harmonization info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Antioxidants 9 1 75 ORIGINAL Oses-antioxidants_2020.pdf Oses-antioxidants_2020.pdf application/pdf 890716 https://riubu.ubu.es/bitstream/10259/5367/1/Oses-antioxidants_2020.pdf 4851f923a9aa817ca36862b3f00eed77 MD5 1 CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 908 https://riubu.ubu.es/bitstream/10259/5367/2/license_rdf 0175ea4a2d4caec4bbcc37e300941108 MD5 2 LICENSE license.txt license.txt text/plain; charset=utf-8 999 https://riubu.ubu.es/bitstream/10259/5367/3/license.txt b295bcbce42e2caabeb0c623d3860c06 MD5 3 THUMBNAIL Oses-antioxidants_2020.pdf.jpg Oses-antioxidants_2020.pdf.jpg IM Thumbnail image/jpeg 4507 https://riubu.ubu.es/bitstream/10259/5367/4/Oses-antioxidants_2020.pdf.jpg 25ccb5ce1cf00c22c3e265a95394a441 MD5 4 TEXT Oses-antioxidants_2020.pdf.txt Oses-antioxidants_2020.pdf.txt Extracted text text/plain 71454 https://riubu.ubu.es/bitstream/10259/5367/5/Oses-antioxidants_2020.pdf.txt d12cb214b8fc69f6c970c3550bd3c30b MD5 5 10259/5367 oai:riubu.ubu.es:10259/5367 2021-11-02 13:02:52.682 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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