2026-04-28T16:38:29Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/53962022-09-29T22:42:07Zcom_10259_4313com_10259_5086com_10259_2604col_10259_4314

Guembe García, Marta Vallejos Calzada, Saúl Carreira Barral, Israel Ibeas Cortes, Saturnino García García, Félix Clemente Santaolalla García, Victoria Moradillo Renuncio, Natalia García Pérez, José Miguel 2020-07-27T10:30:20Z 2020-07-27T10:30:20Z 2020-09 1381-5148 http://hdl.handle.net/10259/5396 10.1016/j.reactfunctpolym.2020.104685 We have developed a new sensory material for the rapid and inexpensive determination of Zn(II), and we have carried out a proof of concept for the determination of Zn(II) in biological samples. The interaction with Zn(II) generates an OFF-ON fluorescence process on the material, which can be recorded both with a fluorimeter and with a smartphone by analyzing the RGB components of the taken photographs. This sensory material is prepared with 99.75% of commercially available monomers and contains 0.25% of a sensory monomer based on a quinoline structure. The sensory motifs are chemically anchored to the polymeric structure, and, accordingly, no migration of organic substances from the material occurs during the sensing process. Our method has been tested with freshly prepared Zn(II) aqueous solutions, but also with biological samples from exudates of chronic wounds. The proposed methodology provides limits of detection (LOD) of 13 and 27 ppb when employing a water-soluble polymer (WsP) and a hydrophilic polymeric film (HP), respectively, using emission spectroscopy. The measurements have been contrasted with ICP-MS as the reference method, obtaining reliable data. This study is the starting point toward a larger investigation with patients, which will address the challenge of establishing a direct relationship between the concentration of zinc(II), other cations and also of amino acids, with the protease activity and, finally, with the state/evolution of chronic wounds. In this context, the proposed sensory material and others we are now working with will act as a simple and cheap method for this purpose. FEDER (Fondo Europeo de Desarrollo Regional), and both the Spanish Ministerio de Economía, Industria y Competitividad (MAT2017-84501-R) and the Consejería de Educación—Junta de Castilla y León (BU061U16) application/pdf eng Elsevier Reactive and Functional Polymers. 2020, V. 154, 104685 https://doi.org/10.1016/j.reactfunctpolym.2020.104685 info:eu-repo/grantAgreement/MINECO/MAT2017-84501-R info:eu-repo/grantAgreement/JCyL/BU061U16 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Smart materials Sensory polymers Zinc(II) detection Biological samples Chronic wounds Química orgánica Chemistry, Organic Zn(II) detection in biological samples with a smart sensory polymer info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Reactive and Functional Polymers 154 104685