2026-04-28T07:05:52Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/54832024-07-24T11:46:38Zcom_10259_9476com_10259.4_106com_10259_2604com_10259_3924com_10259_5086col_10259_9477col_10259_3925

Domi, Brixhilda 791 500 0000-0001-7786-8615 Bhorkar, Kapil e3598e01-5cec-4cfb-bed1-406ae8b1019a 500 Rumbo Lorenzo, Carlos 505 500 0000-0002-5038-0334 Sygellou, Labrini 2c3bf496-8ed4-4640-bbcc-cf086f807e28 500 Yannopoulos, Spyros N. a42c587c-31c0-43bf-9ffb-62ab92f95abf 500 Quesada Pato, Roberto 458 500 0000-0003-2764-7157 Tamayo Ramos, Juan Antonio 547 500 0000-0002-7071-002X 2020-09-24T09:52:56Z 2020-09-24T09:52:56Z 2020-10 0957-4484 http://hdl.handle.net/10259/5483 10.1088/1361-6528/aba6b3 1361-6528 The physicochemical properties and the toxicological potential of commercially available MoS2 nanoparticles with different lateral size and degradation stage were studied in the present research work. To achieve this, the structure and stoichiometry of fresh and old aqueous suspensions of micro-MoS2 and nano-MoS2 was analyzed by Raman, while x-ray photoelectron spectroscopy allowed to identify more quantitatively the nature of the formed oxidized species. A, the toxicological impact of the nanomaterials under analysis was studied using adenocarcinomic human alveolar basal epithelial cells (A549 cells) and the unicellular fungus S. cerevisiae as biological models. Cell viability assays and reactive oxygen species (ROS) determinations demonstrated different toxicity levels depending on the cellular model used and in function of the degradation state of the selected commercial nanoproducts. Both MoS2 nanoparticle types induced sublethal damage on the A549 cells though the increase of intracellular ROS levels, while comparable concentrations reduced the viability of yeast cells. In addition, the old MoS2 nanoparticles suspensions exhibited a higher toxicity for both human and yeast cells than the fresh ones. Our findings demonstrate that the fate assessment of nanomaterials is a critical aspect to increase the understanding on their characteristics and on their potential impact on biological systems along their life cycle. application/pdf eng IOP Publishing Nanotechnology, 2020. V. 31, N. 44, 445101 https://doi.org/10.1088/1361-6528/aba6b3 Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess molybdenum disulfide nanoparticles fate physicochemical composition toxicity oxidative stress cell viability Química orgánica Chemistry, Organic Fate assessment of commercial 2D MoS2 aqueous dispersions at physicochemical and toxicological level info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Nanotechnology 31 44 445101 TEXT Domi-nanotechnology-2020.pdf.txt Domi-nanotechnology-2020.pdf.txt Extracted text text/plain 50137 https://riubu.ubu.es/bitstream/10259/5483/5/Domi-nanotechnology-2020.pdf.txt d0b9c24d6778a3cbd8c3dc46cf9179c7 MD5 5 THUMBNAIL Domi-nanotechnology-2020.pdf.jpg Domi-nanotechnology-2020.pdf.jpg IM Thumbnail image/jpeg 4489 https://riubu.ubu.es/bitstream/10259/5483/4/Domi-nanotechnology-2020.pdf.jpg 5b1c5fdb9ac06025551b4c0df462f694 MD5 4 LICENSE license.txt license.txt text/plain; charset=utf-8 998 https://riubu.ubu.es/bitstream/10259/5483/3/license.txt aa90105e1c90a1b4fe810649aa967b7d MD5 3 CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 908 https://riubu.ubu.es/bitstream/10259/5483/2/license_rdf 0175ea4a2d4caec4bbcc37e300941108 MD5 2 ORIGINAL Domi-nanotechnology-2020.pdf Domi-nanotechnology-2020.pdf application/pdf 4117137 https://riubu.ubu.es/bitstream/10259/5483/1/Domi-nanotechnology-2020.pdf 4a0962e6366979f50ed77c18e166e062 MD5 1 10259/5483 oai:riubu.ubu.es:10259/5483 2024-07-24 13:46:38.358 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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