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<dc:title>One-Pot Synthesis of Enantiopure Pyrrolopiperazines</dc:title>
<dc:creator>Pertejo Fernández, Pablo</dc:creator>
<dc:creator>González Saiz, Beatriz</dc:creator>
<dc:creator>Quesada Pato, Roberto</dc:creator>
<dc:creator>García Valverde, María</dc:creator>
<dc:description>A simple one-pot protocol for the synthesis of fused&#xd;
pyrrolopiperazines with a complete diastereoselectivity has been&#xd;
developed. This novel methodology combined the Ugi reaction&#xd;
with a spontaneous enamine alkylation on a multicomponent&#xd;
domino reaction, starting from nonprotected diamines and&#xd;
arylglyoxals.</dc:description>
<dc:date>2021-03-16T09:06:09Z</dc:date>
<dc:date>2021-03-16T09:06:09Z</dc:date>
<dc:date>2020-11</dc:date>
<dc:type>info:eu-repo/semantics/article</dc:type>
<dc:identifier>0022-3263</dc:identifier>
<dc:identifier>http://hdl.handle.net/10259/5648</dc:identifier>
<dc:identifier>10.1021/acs.joc.0c02103</dc:identifier>
<dc:identifier>1520-6904</dc:identifier>
<dc:language>eng</dc:language>
<dc:relation>The Journal of Organic Chemistry. 2020, V. 85, n. 21, p. 14240–14245</dc:relation>
<dc:relation>https://doi.org/10.1021/acs.joc.0c02103</dc:relation>
<dc:relation>info:eu-repo/grantAgreement/JCyL/BU075G19</dc:relation>
<dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
<dc:publisher>American Chemical Society</dc:publisher>
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