<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-04-28T17:08:13Z</responseDate><request verb="GetRecord" identifier="oai:riubu.ubu.es:10259/5648" metadataPrefix="qdc">https://riubu.ubu.es/oai/request</request><GetRecord><record><header><identifier>oai:riubu.ubu.es:10259/5648</identifier><datestamp>2021-11-05T23:42:10Z</datestamp><setSpec>com_10259_3924</setSpec><setSpec>com_10259_5086</setSpec><setSpec>com_10259_2604</setSpec><setSpec>col_10259_3925</setSpec></header><metadata><qdc:qualifieddc xmlns:qdc="http://dspace.org/qualifieddc/" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xsi:schemaLocation="http://purl.org/dc/elements/1.1/ http://dublincore.org/schemas/xmls/qdc/2006/01/06/dc.xsd http://purl.org/dc/terms/ http://dublincore.org/schemas/xmls/qdc/2006/01/06/dcterms.xsd http://dspace.org/qualifieddc/ http://www.ukoln.ac.uk/metadata/dcmi/xmlschema/qualifieddc.xsd">
<dc:title>One-Pot Synthesis of Enantiopure Pyrrolopiperazines</dc:title>
<dc:creator>Pertejo Fernández, Pablo</dc:creator>
<dc:creator>González Saiz, Beatriz</dc:creator>
<dc:creator>Quesada Pato, Roberto</dc:creator>
<dc:creator>García Valverde, María</dc:creator>
<dcterms:abstract>A simple one-pot protocol for the synthesis of fused&#xd;
pyrrolopiperazines with a complete diastereoselectivity has been&#xd;
developed. This novel methodology combined the Ugi reaction&#xd;
with a spontaneous enamine alkylation on a multicomponent&#xd;
domino reaction, starting from nonprotected diamines and&#xd;
arylglyoxals.</dcterms:abstract>
<dcterms:dateAccepted>2021-03-16T09:06:09Z</dcterms:dateAccepted>
<dcterms:available>2021-03-16T09:06:09Z</dcterms:available>
<dcterms:created>2021-03-16T09:06:09Z</dcterms:created>
<dcterms:issued>2020-11</dcterms:issued>
<dc:type>info:eu-repo/semantics/article</dc:type>
<dc:identifier>0022-3263</dc:identifier>
<dc:identifier>http://hdl.handle.net/10259/5648</dc:identifier>
<dc:identifier>10.1021/acs.joc.0c02103</dc:identifier>
<dc:identifier>1520-6904</dc:identifier>
<dc:language>eng</dc:language>
<dc:relation>The Journal of Organic Chemistry. 2020, V. 85, n. 21, p. 14240–14245</dc:relation>
<dc:relation>https://doi.org/10.1021/acs.joc.0c02103</dc:relation>
<dc:relation>info:eu-repo/grantAgreement/JCyL/BU075G19</dc:relation>
<dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
<dc:publisher>American Chemical Society</dc:publisher>
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