2026-04-28T15:42:17Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/58452024-07-25T07:32:44Zcom_10259_9476com_10259.4_106com_10259_2604col_10259_9477

Rumbo Lorenzo, Carlos 505 500 0000-0002-5038-0334 Cancho Espina, Cristina 723971f2-0655-4492-9aa7-7368de26598b 500 Gassmann, Jürgen cfbf0da6-d7bf-461d-845f-c03189934f3b 500 Tosoni, Olivier 823df5e8-e934-4a3f-a2bb-271f5413d2dd 500 Barros García, Rocío 787 500 0000-0002-0392-8504 Martel Martín, Sonia 790 500 0000-0001-9080-0877 Tamayo Ramos, Juan Antonio 547 500 0000-0002-7071-002X 2021-07-29T10:18:21Z 2021-07-29T10:18:21Z 2021-06 http://hdl.handle.net/10259/5845 10.1038/s41598-021-91890-0 2045-2322 Due to their exceptional physico-chemical and magnetic characteristics, rare earth (RE) permanent magnets are applied in multiple critical technologies. However, several environmental and economic difficulties arising from obtaining RE elements have prompted the search of alternatives with acceptable magnetic properties but containing a lower percentage of these elements in their composition. The aim of this work was to perform a preliminary toxicological evaluation of three forms of newly developed RE-lean alloys (one NdFeTi and two NdFeSi alloys) applying different in vitro assays, using as a benchmark a commercial NdFeB alloy. Thus, the effects of the direct exposure to powder suspensions and to their derived leachates were analysed in two model organisms (the A549 human cell line and the yeast Saccharomyces cerevisiae) applying both viability and oxidative stress assays. Moreover, the impact of the alloy leachates on the bioluminescence of Vibrio fischeri was also investigated. The obtained data showed that only the direct interaction of the alloys particulates with the applied organisms resulted in harmful effects, having all the alloys a comparable toxicological potential to that presented by the reference material in the conditions tested. Altogether, this study provides new insights about the safety of NdFeTi and NdFeSi alloys. EU Horizon 2020 NOVAMAG project (NMBP 23-2015, Grant Agreement No. 686056) and from the Junta de Castilla y León and the European Social Fund-Youth European Initiative Grant UBU-15-A. application/pdf eng Nature Research Scientific Reports. 2021, V. 11, n. 1, 12633 https://doi.org/10.1038/s41598-021-91890-0 info:eu-repo/grantAgreement/EC/H2020/686056 info:eu-repo/grantAgreement/JCyL/UBU-15-A Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Materiales Materials In vitro safety evaluation of rare earth-lean alloys for permanent magnets manufacturing info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Scientific Reports 11 1 THUMBNAIL Rumbo-sc_2021.pdf.jpg Rumbo-sc_2021.pdf.jpg IM Thumbnail image/jpeg 4766 https://riubu.ubu.es/bitstream/10259/5845/4/Rumbo-sc_2021.pdf.jpg a35750024b87bda938188b8a45b996e8 MD5 4 LICENSE license.txt license.txt text/plain; charset=utf-8 998 https://riubu.ubu.es/bitstream/10259/5845/3/license.txt aa90105e1c90a1b4fe810649aa967b7d MD5 3 CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 908 https://riubu.ubu.es/bitstream/10259/5845/2/license_rdf 0175ea4a2d4caec4bbcc37e300941108 MD5 2 ORIGINAL Rumbo-sc_2021.pdf Rumbo-sc_2021.pdf application/pdf 1692485 https://riubu.ubu.es/bitstream/10259/5845/1/Rumbo-sc_2021.pdf 7f00d2702156551bfa14caaaeb9ab1ef MD5 1 10259/5845 oai:riubu.ubu.es:10259/5845 2024-07-25 09:32:44.234 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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