2026-04-28T18:09:41Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/70862022-10-07T00:05:25Zcom_10259_3924com_10259_5086com_10259_2604col_10259_3925
Base-selective access to highly functionalized heterocycles from multicomponent Ugi adducts
González Saiz, Beatriz
Pertejo Fernández, Pablo
Peña Calleja, Pablo
Mielczarek, Marcin
Hermosilla, Tomás
Carreira Barral, Israel
Miguel, Olivia de
Rodríguez Vidal, Francisco Javier
Quesada Pato, Roberto
García Valverde, María
Química orgánica
Bioquímica
Chemistry, Organic
Biochemistry
Selection of the appropriate base in Ugi/post-condensation sequences allows the selective syntheses of different ring-size functionalized lactams. The developed methodology uses inexpensive bases under mild and non-sensitive conditions leading to the facile generation of molecular diversity from simple synthons.
Funding from Consejería de Educación de la Junta de Castilla y León and European Regional Development Fund (ERDF) (project BU075G19 and project BU067P20) and MCIN/AEI/10.13039/501100011033 [grant PID2020-117610RB-I00] is gratefully acknowledged. B. G.-S. and I. C.-B. thank Consejería de Educación de la Junta de Castilla y León, European Social Fund (ESF) and ERDF for their predoctoral (B. G.-S) and postdoctoral (I. C.-B.) contracts.
2022-10-06T10:00:22Z
2022-10-06T10:00:22Z
2022-09
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
1463-9262
http://hdl.handle.net/10259/7086
10.1039/D2GC02896D
1463-9270
eng
Green Chemistry. 2022,
https://doi.org/10.1039/D2GC02896D
info:eu-repo/grantAgreement/Junta de Castilla y León//BU075G19
info:eu-repo/grantAgreement/Junta de Castilla y León//BU067P20
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-117610RB-I00/ES/SMALL MOLECULE TRANSMEMBRANE ANION CARRIERS FOR BIOLOGICAL APPLICATIONS
Attribution-NonCommercial 3.0 Unported
http://creativecommons.org/licenses/by-nc/3.0/
info:eu-repo/semantics/openAccess
application/pdf
Royal Society of Chemistry