2026-05-12T04:52:03Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/75572023-04-18T12:38:02Zcom_10259_4862com_10259_5086com_10259_2604col_10259_4863
Alves Elois, Mariana
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600
Silva, Raphael da
c8221e60-1bfd-4f1b-9b13-c6203cc5d2f3
600
Pilati, Giulia
06d56c6b-e81f-4a09-ae7c-bcd0a3666e0a
600
Rodríguez Lázaro, David
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600
0000-0002-8795-854X
Fongaro, Gislaine
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600
2023-03-20T08:25:19Z
2023-03-20T08:25:19Z
2023-01
http://hdl.handle.net/10259/7557
10.3390/v15020349
1999-4915
Bacteriophages are ubiquitous organisms that can be specific to one or multiple strains
of hosts, in addition to being the most abundant entities on the planet. It is estimated that they
exceed ten times the total number of bacteria. They are classified as temperate, which means that
phages can integrate their genome into the host genome, originating a prophage that replicates
with the host cell and may confer immunity against infection by the same type of phage; and lytics,
those with greater biotechnological interest and are viruses that lyse the host cell at the end of its
reproductive cycle. When lysogenic, they are capable of disseminating bacterial antibiotic resistance
genes through horizontal gene transfer. When professionally lytic—that is, obligately lytic and not
recently descended from a temperate ancestor—they become allies in bacterial control in ecological
imbalance scenarios; these viruses have a biofilm-reducing capacity. Phage therapy has also been
advocated by the scientific community, given the uniqueness of issues related to the control of
microorganisms and biofilm production when compared to other commonly used techniques. The
advantages of using bacteriophages appear as a viable and promising alternative. This review will
provide updates on the landscape of phage applications for the biocontrol of pathogens in industrial
settings and healthcare.
This study was funded by CNPQ and the Federal University of Santa Catarina, SIGPEX UFSC–201917940.
application/pdf
eng
MDPI
Viruses. 2023, V. 15, n. 2, 349
https://doi.org/10.3390/v15020349
info:eu-repo/grantAgreement/UFSC//201917940/BR/
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
Bacteriophages
Applications
Biotechnological
Microbiología
Microbiology
Bacteriophages as Biotechnological Tools
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Viruses
15
2
THUMBNAIL
Alves-viruses_2023.pdf.jpg
Alves-viruses_2023.pdf.jpg
IM Thumbnail
image/jpeg
3380
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LICENSE
license.txt
license.txt
text/plain; charset=utf-8
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https://riubu.ubu.es/bitstream/10259/7557/3/license.txt
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CC-LICENSE
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ORIGINAL
Alves-viruses_2023.pdf
Alves-viruses_2023.pdf
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https://riubu.ubu.es/bitstream/10259/7557/1/Alves-viruses_2023.pdf
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MD5
1
10259/7557
oai:riubu.ubu.es:10259/7557
2023-04-18 14:38:02.585
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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