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<dc:creator>Clemente-Suárez, Vicente Javier</dc:creator>
<dc:creator>Mielgo Ayuso, Juan</dc:creator>
<dc:creator>Martín-Rodríguez, Alexandra</dc:creator>
<dc:creator>Ramos-Campo, Domingo Jesús</dc:creator>
<dc:creator>Redondo-Flórez, Laura</dc:creator>
<dc:creator>Tornero-Aguilera, José Francisco</dc:creator>
<dc:date>2022-09</dc:date>
<dc:description>Foods high in carbohydrates are an important part of a healthy diet, since they provide&#xd;
the body with glucose to support bodily functions and physical activity. However, the abusive&#xd;
consumption of refined, simple, and low-quality carbohydrates has a direct implication on the&#xd;
physical and mental pathophysiology. Then, carbohydrate consumption is postulated as a crucial&#xd;
factor in the development of the main Western diseases of the 21st century. We conducted this&#xd;
narrative critical review using MedLine (Pubmed), Cochrane (Wiley), Embase, and CinAhl databases&#xd;
with the MeSH-compliant keywords: carbohydrates and evolution, development, phylogenetic,&#xd;
GUT, microbiota, stress, metabolic health, consumption behaviors, metabolic disease, cardiovascular&#xd;
disease, mental disease, anxiety, depression, cancer, chronic kidney failure, allergies, and asthma&#xd;
in order to analyze the impact of carbohydrates on health. Evidence suggests that carbohydrates,&#xd;
especially fiber, are beneficial for the well-being and growth of gut microorganisms and consequently&#xd;
for the host in this symbiotic relationship, producing microbial alterations a negative effect on mental&#xd;
health and different organic systems. In addition, evidence suggests a negative impact of simple&#xd;
carbohydrates and refined carbohydrates on mood categories, including alertness and tiredness,&#xd;
reinforcing a vicious circle. Regarding physical health, sugar intake can affect the development and&#xd;
prognosis of metabolic disease, as an uncontrolled intake of refined carbohydrates puts individuals&#xd;
at risk of developing metabolic syndrome and subsequently developing metabolic disease.</dc:description>
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<dc:identifier>http://hdl.handle.net/10259/7573</dc:identifier>
<dc:language>eng</dc:language>
<dc:publisher>MDPI</dc:publisher>
<dc:title>The Burden of Carbohydrates in Health and Disease</dc:title>
<dc:type>info:eu-repo/semantics/article</dc:type>
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