2026-04-17T20:33:37Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/76102023-03-30T00:05:26Zcom_10259_6256com_10259_5086com_10259_2604com_10259_4141col_10259_6257col_10259_4142

Fernández-Araque, Ana Verde, Zoraida Torres-Ortega, Clara Sainz-Gil, María Velasco-González, Verónica González Bernal, Jerónimo Mielgo Ayuso, Juan 2023-03-29T07:52:41Z 2023-03-29T07:52:41Z 2022-04 http://hdl.handle.net/10259/7610 10.3390/jcm11092462 2077-0383 In recent years, antioxidant supplements have become popular to counteract the effects of oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. The aim of this systematic review was to summarize the effects of antioxidant supplementation on pain levels perceived by patients diagnosed with fibromyalgia. The words used respected the medical search terms related to our objective including antioxidants, fibromyalgia, pain, and supplementation. Seventeen relevant articles were identified within Medline (PubMed), Scopus, Web of Science (WOS), the Cochrane Database of Systematic Review, and the Cochrane Central Register of Controlled Trials. This review found that antioxidant supplementation is efficient in reducing pain in nine of the studies reviewed. Studies with a duration of supplementation of at least 6 weeks showed a benefit on pain perception in 80% of the patients included in these studies. The benefits shown by vitamins and coenzyme Q10 are remarkable. Further research is needed to identify the effects of other types of antioxidants, such as extra virgin olive oil and turmeric. More homogeneous interventions in terms of antioxidant doses administered and duration would allow the effects on pain to be addressed more comprehensively. eng MDPI Journal of Clinical Medicine. 2022, V. 11, n. 9, 2462 https://doi.org/10.3390/jcm11092462 Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Antioxidants Fibromyalgia Pain Supplementation Systematic review Fisiología Psicología Salud Physiology Psychology Health Effects of Antioxidants on Pain Perception in Patients with Fibromyalgia—A Systematic Review info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Journal of Clinical Medicine 11 9