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<dc:creator>Fernández-Araque, Ana</dc:creator>
<dc:creator>Verde, Zoraida</dc:creator>
<dc:creator>Torres-Ortega, Clara</dc:creator>
<dc:creator>Sainz-Gil, María</dc:creator>
<dc:creator>Velasco-González, Verónica</dc:creator>
<dc:creator>González Bernal, Jerónimo</dc:creator>
<dc:creator>Mielgo Ayuso, Juan</dc:creator>
<dc:date>2022-04</dc:date>
<dc:description>In recent years, antioxidant supplements have become popular to counteract the effects&#xd;
of oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. The aim of&#xd;
this systematic review was to summarize the effects of antioxidant supplementation on pain levels&#xd;
perceived by patients diagnosed with fibromyalgia. The words used respected the medical search&#xd;
terms related to our objective including antioxidants, fibromyalgia, pain, and supplementation.&#xd;
Seventeen relevant articles were identified within Medline (PubMed), Scopus, Web of Science (WOS),&#xd;
the Cochrane Database of Systematic Review, and the Cochrane Central Register of Controlled Trials.&#xd;
This review found that antioxidant supplementation is efficient in reducing pain in nine of the studies&#xd;
reviewed. Studies with a duration of supplementation of at least 6 weeks showed a benefit on pain&#xd;
perception in 80% of the patients included in these studies. The benefits shown by vitamins and&#xd;
coenzyme Q10 are remarkable. Further research is needed to identify the effects of other types of&#xd;
antioxidants, such as extra virgin olive oil and turmeric. More homogeneous interventions in terms&#xd;
of antioxidant doses administered and duration would allow the effects on pain to be addressed more&#xd;
comprehensively.</dc:description>
<dc:identifier>http://hdl.handle.net/10259/7610</dc:identifier>
<dc:language>eng</dc:language>
<dc:publisher>MDPI</dc:publisher>
<dc:title>Effects of Antioxidants on Pain Perception in Patients with Fibromyalgia—A Systematic Review</dc:title>
<dc:type>info:eu-repo/semantics/article</dc:type>
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