2026-04-17T20:36:51Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/76102023-03-30T00:05:26Zcom_10259_6256com_10259_5086com_10259_2604com_10259_4141col_10259_6257col_10259_4142
Effects of Antioxidants on Pain Perception in Patients with Fibromyalgia—A Systematic Review
Fernández-Araque, Ana
Verde, Zoraida
Torres-Ortega, Clara
Sainz-Gil, María
Velasco-González, Verónica
González Bernal, Jerónimo
Mielgo Ayuso, Juan
Antioxidants
Fibromyalgia
Pain
Supplementation
Systematic review
Fisiología
Psicología
Salud
Physiology
Psychology
Health
In recent years, antioxidant supplements have become popular to counteract the effects
of oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. The aim of
this systematic review was to summarize the effects of antioxidant supplementation on pain levels
perceived by patients diagnosed with fibromyalgia. The words used respected the medical search
terms related to our objective including antioxidants, fibromyalgia, pain, and supplementation.
Seventeen relevant articles were identified within Medline (PubMed), Scopus, Web of Science (WOS),
the Cochrane Database of Systematic Review, and the Cochrane Central Register of Controlled Trials.
This review found that antioxidant supplementation is efficient in reducing pain in nine of the studies
reviewed. Studies with a duration of supplementation of at least 6 weeks showed a benefit on pain
perception in 80% of the patients included in these studies. The benefits shown by vitamins and
coenzyme Q10 are remarkable. Further research is needed to identify the effects of other types of
antioxidants, such as extra virgin olive oil and turmeric. More homogeneous interventions in terms
of antioxidant doses administered and duration would allow the effects on pain to be addressed more
comprehensively.
2023-03-29T07:52:41Z
2023-03-29T07:52:41Z
2022-04
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://hdl.handle.net/10259/7610
10.3390/jcm11092462
2077-0383
eng
Journal of Clinical Medicine. 2022, V. 11, n. 9, 2462
https://doi.org/10.3390/jcm11092462
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
MDPI
https://riubu.ubu.es/bitstream/10259/7610/4/Fernandez-jcm_2022.pdf.jpg
Hispana
TEXT
http://creativecommons.org/licenses/by/4.0/
RIUBU. Repositorio Institucional de la Universidad de Burgos
http://hdl.handle.net/10259/7610