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oai:riubu.ubu.es:10259/86072024-02-07T07:26:32Zcom_10259_3592com_10259_3591com_10259.4_106com_10259_2604com_10259_3924com_10259_5086col_10259_3930col_10259_3925

Synthesis of Tetrahydronaphthoazetidinones, 2,5‐Dioxo‐1,4‐methanobenzoazepines and 3‐Hydroxypyrrolidinones Through Copper‐Assisted Post‐Ugi Reactions Gómez Ayuso, Javier Lezcano, Mario Carreira Barral, Israel González Saiz, Beatriz Quesada Pato, Roberto García Valverde, María Multicomponent reactions Radical reactions Copper Lactams Post-Ugi reactions Química orgánica Chemistry, Organic Copper-assisted post-Ugi reactions enable access to different heterocyclic systems, tetrahydronaphthoazetidinone, 2,5-dioxo-1,4-methanobenzoazepine and 3-hydroxypyrrolidinone derivatives. The described process affords complex scaffolds from readily available acyclic precursors using simple protocols. Funding from Consejería de Educación de la Junta de Castilla y León and European Regional Development Fund (ERDF) (project BU075G19 and project BU067P20), and MCIN/AEI/10.13039/501100011033 [grant PID2020-117610RB−I00], is gratefully acknowledged. J. G.-A., B. G.-S., and I. C.-B. thank Consejería de Educación de la Junta de Castilla y León, European Social Fund (ESF) and ERDF for their predoctoral (J. G.-A. and B. G.-S.) and post-doctoral (I. C.-B.) contracts. 2024-02-06T13:16:37Z 2024-02-06T13:16:37Z 2023-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 1615-4150 http://hdl.handle.net/10259/8607 10.1002/adsc.202300662 1615-4169 eng Advanced Synthesis & Catalysis. 2023, V. 365, n. 21, p. 3658-3665 https://doi.org/10.1002/adsc.202300662 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess application/pdf Wiley https://riubu.ubu.es/bitstream/10259/8607/4/Gomez-asc_2023.pdf.jpg Hispana TEXT http://creativecommons.org/licenses/by-nc-nd/4.0/ RIUBU. Repositorio Institucional de la Universidad de Burgos http://hdl.handle.net/10259/8607