2026-04-28T07:02:36Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/86092024-02-08T01:05:34Zcom_10259_3592com_10259_3591com_10259.4_106com_10259_2604com_10259_3924com_10259_5086col_10259_3930col_10259_3925

00925njm 22002777a 4500 dc Alonso Carrillo, Daniel author Carreira Barral, Israel author Mielczarek, Marcin author Sancho Medina, Andrea author Herran, Enara author Vairo, Claudia author Pozo, Ángel del author Luzuriaga, Iris author Lazcanoiturburu, Nerea author Ibarrola, Oihane author Ponce, Sara author Villar Vidal, María author García Valverde, María author Quesada Pato, Roberto author 2023-08 Six novel click-tambjamines (1–6) bearing an alkyl chain of varying length linked to the imine moiety have been formulated in nanostructured lipid carriers (NLCs) to evaluate their transmembrane anion transport activity both when free (i.e., not encapsulated) and nanoformulated. Nanostructured lipid carriers (NLCs) are an example of drug delivery systems (DDSs) that stand out because of their versatility. In this work we show that NLCs can be used to efficiently formulate highly lipophilic anionophores and experiments conducted in model liposomes reveal that these formulations are adequate to deliver anionophores without compromising their transport activity. This result paves the way to facilitate the study of highly lipophilic anionophores and their potential use as future drugs. 1477-0520 http://hdl.handle.net/10259/8609 10.1039/D3OB01182H 1477-0539 Formulation and evaluation of anion transporters in nanostructured lipid carriers