2026-04-28T08:52:29Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/86302025-01-22T10:18:45Zcom_10259_9895com_10259_3989com_10259.4_106com_10259_2604col_10259_9896
Similarities between the Effects of Prenatal Chlorpyrifos and Valproic Acid on Ultrasonic Vocalization in Infant Wistar Rats
Morales Navas, Miguel
Castaño Castaño, Sergio
Pérez Fernández, Cristian
Sánchez Gil, Ainhoa
Colomina, María Teresa
Leinekugel, Xavier
Sánchez Santed, Fernando
Autistic spectrum disorder
Ultrasonic vocalizations
Chlorpyrifos
Valproic acid
Prenatal exposure
Autism
Organophosphates
Psicología
Salud
Fisiología
Psychology
Health
Physiology
In recent years, ultrasonic vocalizations (USV) in pups has become established
as a good tool for evaluating behaviors related to communication deficits and emotional states observed
in autism spectrum disorder (ASD). Prenatal valproic acid (VPA) exposure leads to impairments and
social behavior deficits associated with autism, with the effects of VPA being considered as a reliable
animal model of ASD. Some studies also suggest that prenatal exposure to chlorpyrifos (CPF) could
enhance autistic-like behaviors
This research was funded by two grants from the Ministerio de Economía y Competitividad, Spanish Government and the Fondo Europeo de Desarrollo Regional (MINECO-FEDER). Grant numbers: PSI2017-86847-C2-1-R MINECO-FEDER and PSI2017-86847-C2-2-R.
2024-02-08T10:56:01Z
2024-02-08T10:56:01Z
2020-09
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
1661-7827
http://hdl.handle.net/10259/8630
10.3390/ijerph17176376
1660-4601
eng
International Journal of Environmental Research and Public Health. 2020, V. 17, n. 17, p. 1-11
https://doi.org/10.3390/ijerph17176376
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
application/pdf
MDPI