2026-06-01T09:19:14Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/87852024-03-09T01:05:24Zcom_10259_4219com_10259_5086com_10259_2604col_10259_4220

Hernández Gallego, Jesús 46ab3be1-9aaf-49e1-8288-2ec7314551a5 600 Llamas Velasco, Sara 393131e7-2c50-4c78-ade6-7b0269a84404 600 Bermejo Pareja, Félix 1c98fed3-1c4d-4d05-9616-a8f6dc44bf10 600 Vega, Saturio 67b1af25-d275-4e86-8e35-ead499800719 600 Tapias Merino, Ester 025b57e2-afa5-447f-8d9f-83a5748f2c1f 600 Rodríguez Sánchez, Emiliano 7ff080a3-36a8-412f-8be1-900d5fc5836e 600 Boycheva, Elina 076d6474-56be-4c05-bdd0-55bc4d418451 600 Serrano, José Ignacio 40247752-6327-4250-9dd5-af0eaedbfe7b 600 Gil García, Juan Francisco 8affc896-f90e-40a3-be79-630f78a792e8 600 Trincado, Rocío b8cbda89-6fcf-43ed-a921-8931667eb959 600 Vizcaino Sánchez-Rodrigo, José María 0b8d93b5-97cc-461b-992d-05aab7bff120 600 Cacho, Jesús 387700b8-e1ec-4faf-a2b0-11b5bcaef39a 600 Contador, Israel e6e16ab1-1ad9-4233-9e31-b4b51b1bef54 600 García Ptacek, Sara 0e93ce06-e0c2-4998-b1eb-e302a51dc4f0 600 Sierra Hidalgo, Fernando d78480d1-25ad-44f6-9d93-cafcd27acd2c 600 Cubo Delgado, Esther 131 600 0000-0003-0018-1182 Carro, Eva 78f16910-017c-4382-b80c-5cdadc7c7582 600 Villarejo Galende, Alberto 4afc344d-aa03-450d-9960-b770298080ed 600 García García-Patino, Rosalía 114a9492-4cda-43f7-90a9-9e99a7a26647 600 Benito-León, Julián 72bbe682-1b66-4281-bd1c-19eba8634784 600 2024-03-08T12:15:16Z 2024-03-08T12:15:16Z 2019-01 http://hdl.handle.net/10259/8785 doi:10.2196/10941 1929-0748 Background: The Neurological Disorders in Central Spain, second survey (NEDICES-2) is a population-based, closed-cohort study that will include over 8000 subjects aged ≥55 years. It will also include a biobank. Objective: The objective of this study was to evaluate all major aspects of the NEDICES-2 (methods, database, screening instruments, and questionnaires, as well as interexpert rating of the neurological diagnoses) in each one of the planned areas (all of them in central Spain) and to test the possibility of obtaining biological samples from each participant. Methods: A selection of patients and participants of the planned NEDICES-2 underwent face-to-face interviews including a comprehensive questionnaire on demographics, current medications, medical conditions, and lifestyle habits. Biological samples (blood, saliva, urine, and hair) were also obtained. Furthermore, every participant was examined by a neurologist. Results: In this pilot study, 567 study participants were enrolled (196 from hospitals and 371 from primary care physician lists). Of these 567, 310 completed all study procedures (questionnaires and the neurological evaluation). The study was time-consuming for several primary care physicians. Hence, a few primary care physicians from some areas refused to participate, which led to a reconfiguration of study areas. In addition, the central biobank needed to be supplemented by the biobanks of local Spanish National Health System hospitals. Conclusions: Population-based epidemiological surveys, such as the NEDICES-2, require a pilot study to evaluate the feasibility of all aspects of a future field study (population selection, methods and instruments to be used, neurological diagnosis agreement, and data collection). application/pdf eng JMIR Publications JMIR Research Protocols. 2019, V. 8, n. 1, e10941 https://www.researchprotocols.org/2019/1/e10941/ Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Dementia Essential tremor Headache Longitudinal study Mild cognitive impairment NEDICES Observational study Parkinson’s disease Pilot study Population-based study Stroke Sistema nervioso-Enfermedades Neurología Medicina Nervous system-Diseases Neurology Medicine Neurological Disorders in Central Spain, Second Survey: Feasibility Pilot Observational Study info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion JMIR Research Protocols 8 1 THUMBNAIL Hernandez-jmir_2019.pdf.jpg Hernandez-jmir_2019.pdf.jpg IM Thumbnail image/jpeg 4524 https://riubu.ubu.es/bitstream/10259/8785/4/Hernandez-jmir_2019.pdf.jpg 4c5455c6bc3312244cf2b733edfdbdc2 MD5 4 LICENSE license.txt license.txt text/plain; charset=utf-8 999 https://riubu.ubu.es/bitstream/10259/8785/3/license.txt b295bcbce42e2caabeb0c623d3860c06 MD5 3 CC-LICENSE license_rdf license_rdf application/rdf+xml; charset=utf-8 908 https://riubu.ubu.es/bitstream/10259/8785/2/license_rdf 0175ea4a2d4caec4bbcc37e300941108 MD5 2 ORIGINAL Hernandez-jmir_2019.pdf Hernandez-jmir_2019.pdf application/pdf 192742 https://riubu.ubu.es/bitstream/10259/8785/1/Hernandez-jmir_2019.pdf b68668054e3cc054f4abdf4cf4f0ccd8 MD5 1 10259/8785 oai:riubu.ubu.es:10259/8785 2024-03-09 02:05:24.596 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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