2026-06-01T08:50:52Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/88032024-03-13T01:05:30Zcom_10259_4219com_10259_5086com_10259_2604col_10259_4220
Santos García, Diego
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Suárez Castro, Ester
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Deus-Fonticoba, Teresa de
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Feal Panceiras, M. J.
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Muñoz Enríquez, J. G.
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Paz González, José Manuel
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Cores Bartolomé, Carlos
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Planellás, Lluis L.
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García Caldentey, Juan
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Caballol, Núria
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Legarda, Inés
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Cabo López, Iria
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López Manzanares, Lydia
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Ávila Rivera, María A.
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Catalán, María José
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Nogueira, Víctor
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Borrue, Carmen
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Álvarez Saúco, María
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Vela Desojo, Lydia
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Cubo Delgado, Esther
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600
0000-0003-0018-1182
Martínez Castrillo, Juan Carlos
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600
Sánchez Alonso, Pilar
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Alonso Losada, María Gema
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López Ariztegui, Nuria
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Gastón, Itziar
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600
Kulisevsky Bojarsky, Jaume
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600
Pagonabarraga, Javier
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Seijo, Manuel
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Ruíz Martínez, Javier
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600
Valero, Caridad
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Kurtis, Mónica M.
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600
González Ardura, Jessica
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Prieto, Cristina
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Mir, Pablo
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Martínez Martín, Pablo
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COPPADIS Study Group
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2024-03-12T08:29:39Z
2024-03-12T08:29:39Z
2020-10
0891-9887
http://hdl.handle.net/10259/8803
10.1177/0891988720964250
1552-5708
Introduction:
The aim of the present study was to examine the frequency of self-reported sleep problems and their associated factors in a large cohort of PD patients.
Methods:
PD patients and controls, recruited from 35 centers of Spain from the COPPADIS cohort were included in this cross-sectional study. Sleep problems were assessed by the Spanish version of the Parkinson’s disease Sleep Scale version 1 (PDSS-1). An overall score below 82 or a score below 5 on at least 1 item was defined as sleep problems.
Results:
The frequency of sleep problems was nearly double in PD patients compared to controls: 65.8% (448/681) vs 33.5% (65/206) (p < 0.0001). Mean total PDSS score was lower in PD patients than controls: 114.9 ± 28.8 vs 132.8 ± 16.3 (p < 0.0001). Quality of life (QoL) was worse in PD patients with sleep problems compared to those without: PDQ-39SI, 19.3 ± 14 vs 13 ± 11.6 (p < 0.0001); EUROHIS-QoL8, 3.7 ± 0.5 vs 3.9 ± 0.5 (p < 0.0001). Non-motor symptoms burden (NMSS; OR = 1.029; 95%CI 1.015–1.043; p < 0.0001) and impulse control behaviors (QUIP-RS; OR = 1.054; 95%CI 1.009–1.101; p = 0.018) were associated with sleep problems after adjustment for age, gender, disease duration, daily equivalent levodopa dose, H&Y, UPDRS-III, UPDRS-IV, PD-CRS, BDI-II, NPI, VAS-Pain, VAFS, FOGQ, and total number of non-antiparkinsonian treatments.
Conclusion:
Sleep problems were frequent in PD patients and were related to both a worse QoL and a greater non-motor symptoms burden in PD. These findings call for increased awareness of sleep problems in PD patients.
application/pdf
eng
SAGE Publications
Journal of Geriatric Psychiatry and Neurology. 2021, V. 34, n. 6, p. 642-658
https://doi.org/10.1177/0891988720964250
Non-motor symptoms
Parkinson’s disease
Parkinson’s disease sleep scale
Quality of life
Sleep
Sistema nervioso-Enfermedades
Medicina
Neurología
Nervous system-Diseases
Medicine
Neurology
Sleep Problems Are Related to a Worse Quality of Life and a Greater Non-Motor Symptoms Burden in Parkinson’s Disease
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/openAccess
Journal of Geriatric Psychiatry and Neurology
34
6
642
658
THUMBNAIL
Santos-jgpn_2021.pdf.jpg
Santos-jgpn_2021.pdf.jpg
IM Thumbnail
image/jpeg
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https://riubu.ubu.es/bitstream/10259/8803/3/Santos-jgpn_2021.pdf.jpg
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LICENSE
license.txt
license.txt
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https://riubu.ubu.es/bitstream/10259/8803/2/license.txt
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ORIGINAL
Santos-jgpn_2021.pdf
Santos-jgpn_2021.pdf
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https://riubu.ubu.es/bitstream/10259/8803/1/Santos-jgpn_2021.pdf
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10259/8803
oai:riubu.ubu.es:10259/8803
2024-03-13 02:05:30.966
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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