2026-04-28T21:57:50Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/88252024-03-15T01:05:25Zcom_10259_4219com_10259_5086com_10259_2604col_10259_4220
Santos García, Diego
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Deus-Fonticoba, Teresa de
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Cores Bartolomé, Carlos
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Feal Painceiras, María
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García Díaz, Iago
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600
Íñiguez Alvarado, María Cristina
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600
Paz González, José Manuel
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Jesús, Silvia
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Cosgaya, Marina
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García Caldentey, Juan
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Caballol, Núria
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Legarda, Inés
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Hernández Vara, Jorge
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Cabo López, Iria
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López Manzanares, Lydia
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González Aramburu, Isabel
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Ávila Rivera, María A.
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Gómez Mayordomo, Víctor
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Nogueira, Víctor
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Dotor, Julio
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Borrue, Carmen
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Solano Vila, Berta
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Álvarez Saúco, María
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Vela Desojo, Lydia
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Escalante Arroyo, Sonia
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Cubo Delgado, Esther
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Mendoza, Zebenzui
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Martínez Castrillo, Juan Carlos
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Sánchez Alonso, Pilar
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Alonso Losada, María Gema
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López Ariztegui, Nuria
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Gastón, Itziar
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Kulisevsky Bojarsky, Jaume
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Seijo, Manuel
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Valero, Caridad
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Alonso Redondo, Rubén
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Buongiorno, María Teresa
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Ordás Bandera, Carlos Manuel
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Menéndez González, Manuel
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McAfee, Darrian
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Martínez Martín, Pablo
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Mir, Pablo
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COPPADIS Study Group
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2024-03-14T12:56:10Z
2024-03-14T12:56:10Z
2023-11
2162-3279
http://hdl.handle.net/10259/8825
10.1002/brb3.3295
2162-3279
Background and objective: Recently, we demonstrated that staging Parkinson's disease (PD) with a novel simple classification called MNCD, based on four axes (motor, non-motor, cognition, and dependency) and five stages, correlated with disease severity and patients’ quality of life. Here, we analyzed the correlation of MNCD staging with PD caregiver's status.
Patients and methods: Data from the baseline visit of PD patients and their principal caregiver recruited from 35 centers in Spain from the COPPADIS cohort from January 2016 to November 2017 were used to apply the MNCD total score (from 0 to 12) and MNCD stages (from 1 to 5) in this cross-sectional analysis. Caregivers completed the Zarit Caregiver Burden Inventory (ZCBI), Caregiver Strain Index (CSI), Beck Depression Inventory-II (BDI-II), PQ-10, and EUROHIS-QOL 8-item index (EUROHIS-QOL8).
Results: Two hundred and twenty-four PD patients (63 ± 9.6 years old; 61.2% males) and their caregivers (58.5 ± 12.1 years old; 67.9% females) were included. The frequency of MNCD stages was 1, 7.6%; 2, 58.9%; 3, 31.3%; and 4–5, 2.2%. A more advanced MNCD stage was associated with a higher score on the ZCBI (p < .0001) and CSI (p < .0001), and a lower score on the PQ-10 (p = .001), but no significant differences were observed in the BDI-II (p = .310) and EUROHIS-QOL8 (p = .133). Moderate correlations were observed between the MNCD total score and the ZCBI (r = .496; p < .0001), CSI (r = .433; p < .0001), and BDI-II (r = .306; p < .0001) in caregivers.
Conclusion: Staging PD according to the MNCD classification is correlated with caregivers’ strain and burden.
application/pdf
eng
Wiley
Brain and Behavior. 2023, V. 13, n. 12
https://doi.org/10.1002/brb3.3295
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
Burden
Caregiver
Non-motor symptoms
Parkinson’s disease
Stage
Sistema nervioso-Enfermedades
Medicina
Neurología
Nervous system-Diseases
Medicine
Neurology
Staging Parkinson's disease according to the MNCD classification correlates with caregiver burden
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Brain and Behavior
13
12
THUMBNAIL
Santos-bb_2023.pdf.jpg
Santos-bb_2023.pdf.jpg
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3470
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LICENSE
license.txt
license.txt
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https://riubu.ubu.es/bitstream/10259/8825/3/license.txt
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CC-LICENSE
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https://riubu.ubu.es/bitstream/10259/8825/2/license_rdf
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ORIGINAL
Santos-bb_2023.pdf
Santos-bb_2023.pdf
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https://riubu.ubu.es/bitstream/10259/8825/1/Santos-bb_2023.pdf
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10259/8825
oai:riubu.ubu.es:10259/8825
2024-03-15 02:05:25.487
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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