2026-04-21T08:58:55Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/93252024-07-02T00:05:30Zcom_10259_3596com_10259_5086com_10259_2604com_10259_3593col_10259_3597col_10259_3594
Hernández Ruiz, Raquel
277
600
0000-0001-5018-0845
Gómez Gil, Sara
c17cf50a-843a-443e-92b1-6a5607b46351
600
Pedrosa Sáez, María de los Remedios
422
600
0000-0001-7083-8093
Suarez Pantiga, Samuel
544
600
0000-0002-4249-7807
Sanz Díez, Roberto
531
600
0000-0003-2830-0892
2024-07-01T06:55:37Z
2024-07-01T06:55:37Z
2023-09-08
1477-0520
http://hdl.handle.net/10259/9325
10.1039/D3OB01187A
1477-0539
Herein, we report the direct synthesis of a wide variety of functionalized aromatic bromides, chlorides, iodides, and fluorides from nitroarenes in a sequential one-pot operation. This protocol is based on an air- and moisture-tolerant dioxomolybdenum-catalyzed reduction of nitroaromatics, employing pinacol as a reducing agent, which enables subsequent diazotization and halogenation steps. This methodology represents a step-economical, practical, and alternative procedure for synthesizing haloaromatics directly from nitroaromatics.
We gratefully acknowledge the Ministerio de Ciencia e Innovación MCIN/AEI/10.13039/501100011033 (PID2020-115789GB-C21) and the Junta de Castilla y León and FEDER (BU049P20) for financial support. R. H.-R. and S. G.-G. thank the Ministerio de Educación for FPU predoctoral contracts. S. S.-P. thanks the Ministerio de Ciencia e Innovación and the “NextGenerationEU”/PRTR EU for a Ramón y Cajal contract (RYC2021-031533-I).
application/pdf
eng
Royal Society of Chemistry
Organic & Biomolecular Chemistry. 2023, V. 21, n. 38, p. 7791-7798
https://doi.org/10.1039/D3OB01187A
Atribución-NoComercial 4.0 Internacional
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
Química orgánica
Biología molecular
Chemistry, Organic
Molecular biology
Direct synthesis of haloaromatics from nitroarenes via a sequential one-pot Mo-catalyzed reduction/Sandmeyer reaction
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Organic & Biomolecular Chemistry
21
38
7791
7798
THUMBNAIL
Hernandez-obc_2023.pdf.jpg
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Hernandez-obc_2023.pdf
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oai:riubu.ubu.es:10259/9325
2024-07-02 02:05:30.554
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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